4ZOK

Methylsulfonyl-containing inhibitor bound in the substrate capture site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)

Summary for 4ZOK

• Entry DOI: 10.2210/pdb4zok/pdb
• Related: 3QR9 4GIU 4ZOF 4ZOJ
• Descriptor: Anthranilate phosphoribosyltransferase, MAGNESIUM ION, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, ... (5 entities in total)
• Functional Keywords: inhibitor, complex, lobenzarit-like analogue, tb structural genomics consortium, tbsgc, phosphoribosyltransferase, magnesium binding, phosphoribosylpyrophosphate, prpp, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Mycobacterium tuberculosis H37Ra
• Total number of polymer chains: 2
• Total formula weight: 79092.76

Authors

Evans, G.L.,Baker, E.N.,Lott, J.S.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2015-05-06, release date: 2016-05-11, Last modification date: 2023-09-27)

• Primary citation: Evans, G.L.,Baker, E.N.,Lott, J.S.; Inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD).; To be Published,

Experimental method

X-RAY DIFFRACTION (2.34 Å)