4ZOK

Methylsulfonyl-containing inhibitor bound in the substrate capture site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000162	biological_process	L-tryptophan biosynthetic process
A	0000287	molecular_function	magnesium ion binding
A	0004048	molecular_function	anthranilate phosphoribosyltransferase activity
A	0005829	cellular_component	cytosol
A	0008652	biological_process	amino acid biosynthetic process
A	0009073	biological_process	aromatic amino acid family biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0016763	molecular_function	pentosyltransferase activity
A	0046872	molecular_function	metal ion binding
B	0000162	biological_process	L-tryptophan biosynthetic process
B	0000287	molecular_function	magnesium ion binding
B	0004048	molecular_function	anthranilate phosphoribosyltransferase activity
B	0005829	cellular_component	cytosol
B	0008652	biological_process	amino acid biosynthetic process
B	0009073	biological_process	aromatic amino acid family biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016757	molecular_function	glycosyltransferase activity
B	0016763	molecular_function	pentosyltransferase activity
B	0046872	molecular_function	metal ion binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	22
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00211

Chain	Residue	Details
A	GLY107
A	ASP251
A	GLU252
B	GLY107
B	GLY110
B	THR115
B	ASN117
B	SER119
B	LYS135
B	ASN138
B	GLY147
A	GLY110
B	ARG193
B	ASP251
B	GLU252
A	THR115
A	ASN117
A	SER119
A	LYS135
A	ASN138
A	GLY147
A	ARG193

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