5ZWT

Crystal structure of the S37A mutant of apo-acyl carrier protein from Leishmania major

Summary for 5ZWT

Related2M5R
DescriptorAcyl carrier protein (2 entities in total)
Functional Keywordsleishmania major; acyl carrier protein; fatty acid biosynthesis, lipid binding protein
Biological sourceLeishmania major
Total number of polymer chains2
Total molecular weight18542.97
Authors
Sharma, B.,Arya, R.,Kundu, S.,Makde, R.D. (deposition date: 2018-05-16, release date: 2019-01-16)
Primary citation
Arya, R.,Sharma, B.,Dhembla, C.,Pal, R.K.,Patel, A.K.,Sundd, M.,Ghosh, B.,Makde, R.D.,Kundu, S.
A conformational switch from a closed apo- to an open holo-form equips the acyl carrier protein for acyl chain accommodation.
Biochim Biophys Acta Proteins Proteom, 1867:163-174, 2018
PubMed: 30543875 (PDB entries with the same primary citation)
DOI: 10.1016/j.bbapap.2018.12.001
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.273300 4.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5zwt
no rotation
Molmil generated image of 5zwt
rotated about x axis by 90°
Molmil generated image of 5zwt
rotated about y axis by 90°
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