4ZNX

Crystal structure of the Fyn-SH3 domain in complex with the high affinity peptide APP12

Summary for 4ZNX

• Related: 3UA6 3UA7 4EIK
• Descriptor: Tyrosine-protein kinase Fyn, APP12 (3 entities in total)
• Functional Keywords: beta shandwich, signaling protein
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm: P06241
• Total number of polymer chains: 8
• Total formula weight: 32039.45

Authors

Camara-Artigas, A. (deposition date: 2015-05-05, release date: 2016-06-29, Last modification date: 2016-09-28)

• Primary citation: Andujar-Sanchez, M.,Bacarizo, J.,Camara-Artigas, A.,Martin-Garcia, J.M.,Ortiz-Salmeron, E.; The role of water molecules in the binding of class I and II peptides to the SH3 domain of the Fyn tyrosine kinase.; Acta Crystallogr.,Sect.F, 72:707-712, 2016; PubMed: 27599862; DOI: 110.1107/S2053230X16012310

Experimental method

X-RAY DIFFRACTION (2.1 Å)