Crystal structure of the Fyn-SH3 domain in complex with the high affinity peptide APP12

Summary for 4ZNX

Related4EIK 3UA6 3UA7
DescriptorTyrosine-protein kinase Fyn, APP12 (3 entities in total)
Functional Keywordsbeta shandwich, signaling protein
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm P06241
Total number of polymer chains8
Total molecular weight32039.45
Camara-Artigas, A. (deposition date: 2015-05-05, release date: 2016-06-29, Last modification date: 2016-09-28)
Primary citation
Camara-Artigas, A.,Ortiz-Salmeron, E.,Andujar-Sanchez, M.,Bacarizo, J.,Martin-Garcia, J.M.
The role of water molecules in the binding of class I and II peptides to the SH3 domain of the Fyn tyrosine kinase.
Acta Crystallogr.,Sect.F, 72:707-712, 2016
PubMed: 27599862 (PDB entries with the same primary citation)
DOI: 10.1107/S2053230X16012310
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.229000 8.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-21