PDB: 127 件ウェブページステータス検索Chemie searchBIRD

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3OUZ	Crystal Structure of Biotin Carboxylase-ADP complex from Campylobacter jejuni 分子名称: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, D-MALATE, ... 著者 Maltseva, N, Kim, Y, Makowska-Grzyska, M, Mulligan, R, Papazisi, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2010-09-15 公開日 2010-10-13 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.902 Å) 主引用文献 Crystal Structure of Biotin Carboxylase-ADP complex from Campylobacter jejuni TO BE PUBLISHED
3N6R	CRYSTAL STRUCTURE OF the holoenzyme of PROPIONYL-COA CARBOXYLASE (PCC) 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-CoA carboxylase, alpha subunit, ... 著者 Huang, C.S, Sadre-Bazzaz, K, Tong, L. 登録日 2010-05-26 公開日 2010-08-25 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of the alpha(6)beta(6) holoenzyme of propionyl-coenzyme A carboxylase. Nature, 466, 2010
3JZI	Crystal structure of biotin carboxylase from E. Coli in complex with benzimidazole series 分子名称: 7-amino-2-[(2-chlorobenzyl)amino]-1-{[(1S,2S)-2-hydroxycycloheptyl]methyl}-1H-benzimidazole-5-carboxamide, Biotin carboxylase 著者 Cheng, C, Shipps, G.W, Yang, Z, Sun, B, Kawahata, N, Soucy, K, Soriano, A, Orth, P, Xiao, L, Mann, P, Black, T. 登録日 2009-09-23 公開日 2009-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Discovery and optimization of antibacterial AccC inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
3JZF	Crystal structure of biotin carboxylase from E. Coli in complex with benzimidazoles series 分子名称: 2-[(2-chlorobenzyl)amino]-1-(cyclohexylmethyl)-1H-benzimidazole-5-carboxamide, Biotin carboxylase, CARBONATE ION 著者 Orth, P. 登録日 2009-09-23 公開日 2009-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Discovery and optimization of antibacterial AccC inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
3JRW	Phosphorylated BC domain of ACC2 分子名称: Acetyl-CoA carboxylase 2 著者 Cho, Y.S, Lee, J.I, Shin, D, Kim, H.T, Lee, T.G, Heo, Y.S. 登録日 2009-09-09 公開日 2010-01-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Molecular mechanism for the regulation of human ACC2 through phosphorylation by AMPK Biochem.Biophys.Res.Commun., 391, 2010
3JRX	Crystal structure of the BC domain of ACC2 in complex with soraphen A 分子名称: Acetyl-CoA carboxylase 2, SORAPHEN A 著者 Cho, Y.S, Lee, J.I, Shin, D, Kim, H.T, Lee, T.G, Heo, Y.S. 登録日 2009-09-09 公開日 2010-01-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular mechanism for the regulation of human ACC2 through phosphorylation by AMPK. Biochem.Biophys.Res.Commun., 391, 2010
3HO8	Crystal Structure of S. aureus Pyruvate Carboxylase in complex with Coenzyme A 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, MANGANESE (II) ION, ... 著者 Tong, L, Yu, L.P.C. 登録日 2009-06-01 公開日 2009-06-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A Symmetrical Tetramer for S. aureus Pyruvate Carboxylase in Complex with Coenzyme A. Structure, 17, 2009
3HBL	Crystal Structure of S. aureus Pyruvate Carboxylase T908A Mutant 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... 著者 Tong, L, Yu, L.P.C. 登録日 2009-05-04 公開日 2009-06-30 最終更新日 2021-10-13 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 A Symmetrical Tetramer for S. aureus Pyruvate Carboxylase in Complex with Coenzyme A. Structure, 17, 2009
3HB9	Crystal Structure of S. aureus Pyruvate Carboxylase A610T Mutant 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... 著者 Tong, L, Yu, L.P.C. 登録日 2009-05-04 公開日 2009-06-30 最終更新日 2021-10-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A Symmetrical Tetramer for S. aureus Pyruvate Carboxylase in Complex with Coenzyme A. Structure, 17, 2009
3GLK	The biotin carboxylase (BC) domain of human Acetyl-CoA Carboxylase 2 (ACC2) 分子名称: Acetyl-CoA carboxylase 2 著者 Price, A, Kulathila, R. 登録日 2009-03-12 公開日 2009-03-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Synthesis and characterization of a BODIPY-labeled derivative of Soraphen A that binds to acetyl-CoA carboxylase. Bioorg.Med.Chem.Lett., 19, 2009
3GID	The biotin carboxylase (BC) domain of human Acetyl-CoA Carboxylase 2 (ACC2) in complex with Soraphen A 分子名称: Acetyl-CoA carboxylase 2, SORAPHEN A 著者 Price, A, Kulathila, R. 登録日 2009-03-05 公開日 2009-03-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Synthesis and characterization of a BODIPY-labeled derivative of Soraphen A that binds to acetyl-CoA carboxylase. Bioorg.Med.Chem.Lett., 19, 2009
3G8C	Crystal Structure of Biotin Carboxylase in Complex with Biotin, Bicarbonate, ADP and Mg Ion 分子名称: ADENOSINE-5'-DIPHOSPHATE, BICARBONATE ION, BIOTIN, ... 著者 Chou, C.Y, Yu, L.P, Tong, L. 登録日 2009-02-12 公開日 2009-03-03 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of biotin carboxylase in complex with substrates and implications for its catalytic mechanism. J.Biol.Chem., 284, 2009
3G8D	Crystal structure of the biotin carboxylase subunit, E296A mutant, of acetyl-COA carboxylase from Escherichia coli 分子名称: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, MAGNESIUM ION, ... 著者 Chou, C.Y, Yu, L.P, Tong, L. 登録日 2009-02-12 公開日 2009-03-03 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of biotin carboxylase in complex with substrates and implications for its catalytic mechanism. J.Biol.Chem., 284, 2009
2W6Z	Crystal structure of Biotin carboxylase from E. coli in complex with the 3-(3-Methyl-but-2-enyl)-3H-purin-6-ylamine fragment 分子名称: 3-(3-methylbut-2-en-1-yl)-3H-purin-6-amine, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-12-19 公開日 2009-05-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W71	Crystal structure of Biotin carboxylase from E. coli in complex with the imidazole-pyrimidine inhibitor 分子名称: 4-[1-(2,6-dichlorobenzyl)-2-methyl-1H-imidazol-4-yl]pyrimidin-2-amine, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-12-19 公開日 2009-05-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W70	Crystal structure of Biotin carboxylase from E. coli in complex with the amino-thiazole-pyrimidine fragment 分子名称: 4-(2-amino-1,3-thiazol-4-yl)pyrimidin-2-amine, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-12-19 公開日 2009-05-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6O	Crystal structure of Biotin carboxylase from E. coli in complex with 4-Amino-7,7-dimethyl-7,8-dihydro-quinazolinone fragment 分子名称: 4-amino-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-12-18 公開日 2009-05-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6P	Crystal structure of Biotin carboxylase from E. coli in complex with 5-Methyl-6-phenyl-quinazoline-2,4-diamine 分子名称: 5-methyl-6-phenylquinazoline-2,4-diamine, ACETYL-COA CARBOXYLASE 著者 Mochalkin, I, Miller, J.R. 登録日 2008-12-18 公開日 2009-05-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6M	Crystal structure of Biotin carboxylase from E. coli in complex with amino-oxazole fragment series 分子名称: (2-AMINO-1,3-OXAZOL-5-YL)-(3-BROMOPHENYL)METHANONE, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-12-18 公開日 2009-05-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6N	Crystal structure of Biotin carboxylase from E. coli in complex with amino-oxazole fragment series 分子名称: 2-AMINO-N,N-BIS(PHENYLMETHYL)-1,3-OXAZOLE-5-CARBOXAMIDE, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-12-18 公開日 2009-05-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6Q	Crystal structure of Biotin carboxylase from E. coli in complex with the triazine-2,4-diamine fragment 分子名称: 6-(2-phenoxyethoxy)-1,3,5-triazine-2,4-diamine, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-12-18 公開日 2009-05-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2V59	CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 2 分子名称: 6-(2,6-DIMETHOXYPHENYL)PYRIDO[2,3-D]PYRIMIDINE-2,7-DIAMINE, BIOTIN CARBOXYLASE 著者 Mochalkin, I, Miller, J.R. 登録日 2008-10-02 公開日 2009-01-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore. Proc.Natl.Acad.Sci.USA, 106, 2009
2V58	CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 1 分子名称: 6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-diamine, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-10-02 公開日 2009-01-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore. Proc.Natl.Acad.Sci.USA, 106, 2009
2V5A	CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 3 分子名称: 7-(2,5-dihydropyrrol-1-yl)-6-phenyl-pyrido[6,5-d]pyrimidin-2-amine, BIOTIN CARBOXYLASE, CHLORIDE ION 著者 Mochalkin, I, Miller, J.R. 登録日 2008-10-02 公開日 2009-01-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore. Proc.Natl.Acad.Sci.USA, 106, 2009
2VR1	Crystal structure of Biotin carboxylase from E. coli in complex with ATP analog, ADPCF2P. 分子名称: BIOTIN CARBOXYLASE, CHLORIDE ION, PHOSPHODIFLUOROMETHYLPHOSPHONIC ACID-ADENYLATE ESTER 著者 Mochalkin, I, Waldrop, G.L. 登録日 2008-03-24 公開日 2008-09-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase. Protein Sci., 17, 2008

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