3GLK
The biotin carboxylase (BC) domain of human Acetyl-CoA Carboxylase 2 (ACC2)
Summary for 3GLK
| Entry DOI | 10.2210/pdb3glk/pdb |
| Related | 3GID |
| Descriptor | Acetyl-CoA carboxylase 2 (2 entities in total) |
| Functional Keywords | atp binding, carboxylase, atp-binding, biotin, fatty acid biosynthesis, ligase, lipid synthesis, manganese, membrane, metal-binding, multifunctional enzyme, nucleotide-binding, phosphoprotein, acc2-bc |
| Biological source | Homo sapiens (human) |
| Cellular location | Mitochondrion : O00763 |
| Total number of polymer chains | 1 |
| Total formula weight | 60092.95 |
| Authors | Price, A.,Kulathila, R. (deposition date: 2009-03-12, release date: 2009-03-24, Last modification date: 2024-02-21) |
| Primary citation | Raymer, B.,Kavana, M.,Price, A.,Wang, B.,Corcoran, L.,Kulathila, R.,Groarke, J.,Mann, T. Synthesis and characterization of a BODIPY-labeled derivative of Soraphen A that binds to acetyl-CoA carboxylase. Bioorg.Med.Chem.Lett., 19:2804-2807, 2009 Cited by PubMed: 19359168DOI: 10.1016/j.bmcl.2009.03.107 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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