3JRX
Crystal structure of the BC domain of ACC2 in complex with soraphen A
Summary for 3JRX
Entry DOI | 10.2210/pdb3jrx/pdb |
Related | 2HJW 3JRW |
Descriptor | Acetyl-CoA carboxylase 2, SORAPHEN A (3 entities in total) |
Functional Keywords | bc domain, soraphen a, alternative splicing, atp-binding, biotin, fatty acid biosynthesis, ligase, lipid synthesis, manganese, membrane, metal-binding, multifunctional enzyme, nucleotide-binding, phosphoprotein, polymorphism |
Biological source | Homo sapiens (human) |
Cellular location | Endomembrane system: O00763 |
Total number of polymer chains | 1 |
Total formula weight | 65943.96 |
Authors | |
Primary citation | Cho, Y.S.,Lee, J.I.,Shin, D.,Kim, H.T.,Jung, H.Y.,Lee, T.G.,Kang, L.W.,Ahn, Y.J.,Cho, H.S.,Heo, Y.S. Molecular mechanism for the regulation of human ACC2 through phosphorylation by AMPK. Biochem.Biophys.Res.Commun., 391:187-192, 2010 Cited by PubMed: 19900410DOI: 10.1016/j.bbrc.2009.11.029 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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