3JRX

Crystal structure of the BC domain of ACC2 in complex with soraphen A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Acetyl-CoA carboxylase 2	polymer	587	65423.3	1	UniProt (O00763) Pfam (PF00289) Pfam (PF02786) Pfam (PF02785)	Homo sapiens (human)	ACC-beta, Biotin carboxylase, ACC2
2	B (A)	SORAPHEN A	non-polymer		520.7	1	Chemie (S1A)
3	C (A)	water	water		18.0	93	Chemie (HOH)

Sequence modifications

A: 217 - 775 (UniProt: O00763)

PDB	External Database	Details
Met 205	-	expression tag
Arg 206	-	expression tag
Gly 207	-	expression tag
Ser 208	-	expression tag
Gly 209	-	expression tag
Ser 210	-	expression tag
Met 211	-	expression tag
Arg 212	-	expression tag
Gly 213	-	expression tag
Ser 214	-	expression tag
Gly 215	-	expression tag
Ser 216	-	expression tag
Leu 776	-	expression tag
Glu 777	-	expression tag
His 778	-	expression tag
His 779	-	expression tag
His 780	-	expression tag
His 781	-	expression tag
His 782	-	expression tag
His 783	-	expression tag
Leu 784	-	expression tag
Glu 785	-	expression tag
His 786	-	expression tag
His 787	-	expression tag
His 788	-	expression tag
His 789	-	expression tag
His 790	-	expression tag
His 791	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	65423.3
Non-Polymers*	Number of molecules	1
	Total formula weight	520.7
All*	Total formula weight	65944.0

*Water molecules are not included.