Summary for 2W6M
Related | 2J9G 2VR1 2V5A 1K69 2GPW 2W6N 2W6Q 1BNC 2W71 2V59 2W6P 2W7C 2V58 2W6O 2W6Z 1DV1 2GPS 2W70 1DV2 |
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Descriptor | BIOTIN CARBOXYLASE, (2-AMINO-1,3-OXAZOL-5-YL)-(3-BROMOPHENYL)METHANONE, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | ligase, atp-binding, fatty acid biosynthesis, nucleotide-binding, lipid synthesis, atp-grasp domain, fragment screening |
Biological source | ESCHERICHIA COLI |
Total number of polymer chains | 2 |
Total molecular weight | 99378.38 |
Authors | Mochalkin, I.,Miller, J.R. (deposition date: 2008-12-18, release date: 2009-05-19, Last modification date: 2011-07-13) |
Primary citation | Mochalkin, I.,Miller, J.R.,Narasimhan, L.S.,Thanabal, V.,Erdman, P.,Cox, P.,Prasad, J.V.,Lightle, S.,Huband, M.,Stover, K. Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4:473-, 2009 PubMed: 19413326 (PDB entries with the same primary citation) DOI: 10.1021/CB9000102 ![]() |
Experimental method | X-RAY DIFFRACTION (2 Å) |