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2QE3
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Crystal structure of human tl1a extracellular domain
分子名称: CHLORIDE ION, TNF superfamily ligand TL1A
著者Zhan, C, Yan, Q, Patskovsky, Y, Shi, W, Toro, R, Bonanno, J, Nathenson, S.G, Almo, S.C.
登録日2007-06-22
公開日2007-07-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Biochemical and structural characterization of the human TL1A ectodomain.
Biochemistry, 48, 2009
2QDN
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Crystal Structure of mouse GITRL
分子名称: GITR ligand
著者Chattopadhyay, K, Ramagopal, U.A, Nathenson, S.G, Almo, S.C.
登録日2007-06-21
公開日2008-01-01
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Evolution of GITRL immune function: murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2TNF
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1.4 A RESOLUTION STRUCTURE OF MOUSE TUMOR NECROSIS FACTOR, TOWARDS MODULATION OF ITS SELECTIVITY AND TRIMERISATION
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ISOPROPYL ALCOHOL, PROTEIN (TUMOR NECROSIS FACTOR ALPHA)
著者Baeyens, K.J, De Bondt, H.L, Raeymaekers, A, Fiers, W, De Ranter, C.J.
登録日1998-10-12
公開日1999-10-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The structure of mouse tumour-necrosis factor at 1.4 A resolution: towards modulation of its selectivity and trimerization.
Acta Crystallogr.,Sect.D, 55, 1999
2RE9
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Crystal structure of TL1A at 2.1 A
分子名称: GLYCEROL, MAGNESIUM ION, TNF superfamily ligand TL1A
著者Jin, T.C, Guo, F, Kim, S, Howard, A.J, Zhang, Y.Z.
登録日2007-09-25
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-ray crystal structure of TNF ligand family member TL1A at 2.1 A.
Biochem.Biophys.Res.Commun., 364, 2007
2Q8O
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crystal structure of mouse GITR ligand dimer
分子名称: GITR ligand
著者Zhaocai, Z, Yukiko, T.
登録日2007-06-11
公開日2007-12-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for ligand-mediated mouse GITR activation.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2TUN
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CONFORMATIONAL CHANGES IN THE (ALA-84-VAL) MUTANT OF TUMOR NECROSIS FACTOR
分子名称: TUMOR NECROSIS FACTOR-ALPHA
著者Saludjian, P, Prange, T.
登録日1993-10-06
公開日1994-01-31
最終更新日2013-06-19
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Conformational Changes in the (Ala-84-Val) Mutant of Tumor Necrosis Factor
To be Published
2RJK
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Crystal Structure of Human TL1A Extracellular Domain C95S Mutant
分子名称: TNF superfamily ligand TL1A
著者Zhan, C, Yan, Q, Patskovsky, Y, Shi, W, Ramagopal, U.A, Toro, R, Bonanno, J, Nathenson, S.G, Almo, S.C.
登録日2007-10-15
公開日2008-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Biochemical and structural characterization of the human TL1A ectodomain.
Biochemistry, 48, 2009
2O0O
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Crystal structure of TL1A
分子名称: MAGNESIUM ION, TNF superfamily ligand TL1A
著者Jin, T.C, Kim, S, Guo, F, Howard, A.J, Zhang, Y.Z.
登録日2006-11-27
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray crystal structure of TNF ligand family member TL1A at 2.1A.
Biochem.Biophys.Res.Commun., 364, 2007
2RJL
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Crystal structure of human TL1A extracellular domain C95S/C135S mutant
分子名称: TNF superfamily ligand TL1A
著者Zhan, C, Patskovsky, Y, Yan, Q, Shi, W, Toro, R, Bonanno, J, Nathenson, S.G, Almo, S.C.
登録日2007-10-15
公開日2008-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Biochemical and structural characterization of the human TL1A ectodomain.
Biochemistry, 48, 2009
4V46
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Crystal structure of the BAFF-BAFF-R complex
分子名称: MAGNESIUM ION, Tumor necrosis factor ligand superfamily member 13B, Tumor necrosis factor receptor superfamily member 13C
著者Kim, H.M, Yu, K.S, Lee, M.E, Shin, D.R, Kim, Y.S, Paik, S.G, Yoo, O.J, Lee, H, Lee, J.-O.
登録日2003-03-23
公開日2014-07-09
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of the BAFF-BAFF-R complex and its implications for receptor activation
NAT.STRUCT.BIOL., 10, 2003
3V56
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Re-refinement of PDB entry 1OSG - Complex between BAFF and a BR3 derived peptide presented in a beta-hairpin scaffold - reveals an additonal copy of the peptide.
分子名称: BR3 derived peptive, SULFATE ION, Tumor necrosis factor ligand superfamily member 13B
著者Smart, O.S, Womack, T.O, Flensburg, C, Keller, P, Sharff, A, Paciorek, W, Vonrhein, C, Bricogne, G.
登録日2011-12-16
公開日2012-03-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER.
Acta Crystallogr.,Sect.D, 68, 2012
3IT8
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Crystal structure of TNF alpha complexed with a poxvirus MHC-related TNF binding protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2L protein, Tumor necrosis factor
著者Yang, Z, West Jr, A.P, Bjorkman, P.J.
登録日2009-08-27
公開日2009-10-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of TNFalpha complexed with a poxvirus MHC-related TNF binding protein
Nat.Struct.Mol.Biol., 16, 2009
1OQD
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Crystal structure of sTALL-1 and BCMA
分子名称: Tumor necrosis factor ligand superfamily member 13B, soluble form, Tumor necrosis factor receptor superfamily member 17
著者Zhang, G.
登録日2003-03-07
公開日2003-05-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Ligand-receptor binding revealed by the TNF family member TALL-1.
Nature, 423, 2003
1OQE
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Crystal structure of sTALL-1 with BAFF-R
分子名称: Tumor necrosis factor ligand superfamily member 13B, soluble form, Tumor necrosis factor receptor superfamily member 13C
著者Zhang, G.
登録日2003-03-07
公開日2003-05-13
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Ligand-receptor binding revealed by the TNF family member TALL-1.
Nature, 423, 2003
1XU1
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The crystal structure of APRIL bound to TACI
分子名称: NICKEL (II) ION, Tumor necrosis factor ligand superfamily member 13, Tumor necrosis factor receptor superfamily member 13B
著者Hymowitz, S.G, Patel, D.R, Wallweber, H.J.A, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A.
登録日2004-10-25
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high-affinity ligand binding
J.Biol.Chem., 280, 2005
1XU2
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The crystal structure of APRIL bound to BCMA
分子名称: NICKEL (II) ION, Tumor necrosis factor ligand superfamily member 13, Tumor necrosis factor receptor superfamily member 17
著者Hymowitz, S.G, Patel, D.R, Wallweber, H.J.A, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A.
登録日2004-10-25
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high-affinity ligand binding
J.Biol.Chem., 280, 2005
6CU0
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Crystal structure of 4-1BBL/4-1BB (C121S) complex in P21 space group
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9
著者Aruna, B, Zajonc, D.M, Doukov, T.
登録日2018-03-23
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier.
J. Biol. Chem., 293, 2018
7MSG
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BU of 7msg by Molmil
The crystal structure of LIGHT in complex with HVEM and CD160
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD160 antigen, soluble form,Tumor necrosis factor receptor superfamily member 14, ...
著者Liu, W, Ramagopal, U, Garrett-Thompson, S.C, Fedorov, E, Bonanno, J.B, Almo, S.C.
登録日2021-05-11
公開日2021-10-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160.
J.Exp.Med., 218, 2021
3ALQ
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Crystal structure of TNF-TNFR2 complex
分子名称: COBALT (II) ION, Tumor necrosis factor, Tumor necrosis factor receptor superfamily member 1B
著者Mukai, Y, Nakamura, T, Yamagata, Y, Tsutsumi, Y.
登録日2010-08-06
公開日2010-11-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Solution of the Structure of the TNF-TNFR2 Complex
Sci.Signal., 3, 2010
5BNQ
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Crystal structure of hRANKL-mRANK complex
分子名称: CHLORIDE ION, PHOSPHATE ION, SODIUM ION, ...
著者Ren, J.
登録日2015-05-26
公開日2015-10-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A RANKL mutant used as an inter-species vaccine for efficient immunotherapy of osteoporosis.
Sci Rep, 5, 2015
5CIR
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BU of 5cir by Molmil
Crystal structure of death receptor 4 (DR4; TNFFRSF10A) bound to TRAIL (TNFSF10)
分子名称: CHLORIDE ION, Tumor necrosis factor ligand superfamily member 10, Tumor necrosis factor receptor superfamily member 10A, ...
著者Sheriff, S.
登録日2015-07-13
公開日2017-01-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of the death receptor 4-TNF-related apoptosis-inducing ligand (DR4-TRAIL) complex.
Acta Crystallogr F Struct Biol Commun, 71, 2015
3URF
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Human RANKL/OPG complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 11, soluble form, ...
著者Wang, X.Q, Luan, X.D, Lu, Q.Y.
登録日2011-11-22
公開日2012-07-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.701 Å)
主引用文献Crystal Structure of Human RANKL Complexed with Its Decoy Receptor Osteoprotegerin
J.Immunol., 189, 2012
5L36
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Crystal Structure of a human FasL mutant in complex with human DcR3
分子名称: SODIUM ION, Tumor necrosis factor ligand superfamily member 6, Tumor necrosis factor receptor superfamily member 6B
著者Liu, W, Bonanno, J.B, Almo, S.C.
登録日2016-08-03
公開日2016-09-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of the Complex of Human FasL and Its Decoy Receptor DcR3.
Structure, 24, 2016
3QBQ
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Crystal structure of extracellular domains of mouse RANK-RANKL complex
分子名称: Tumor necrosis factor ligand superfamily member 11, Tumor necrosis factor receptor superfamily member 11A
著者Ta, H.M, Nguyen, G.T.T, Jin, H.M, Choi, J.K, Park, H, Kim, N.S, Hwang, H.Y, Kim, K.K.
登録日2011-01-13
公開日2011-03-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-based development of a receptor activator of nuclear factor-kappaB ligand (RANKL) inhibitor peptide and molecular basis for osteopetrosis
Proc.Natl.Acad.Sci.USA, 107, 2010
3QD6
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Crystal structure of the CD40 and CD154 (CD40L) complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CD40 ligand, Tumor necrosis factor receptor superfamily member 5
著者Lee, J.-O, Kim, Y.J, Song, D.H, Kim, H.M, Park, B.S.
登録日2011-01-18
公開日2011-02-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystallographic and mutational analysis of the CD40-CD154 complex and its implications for receptor activation
J.Biol.Chem., 286, 2011

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