5CIR
Crystal structure of death receptor 4 (DR4; TNFFRSF10A) bound to TRAIL (TNFSF10)
Summary for 5CIR
Entry DOI | 10.2210/pdb5cir/pdb |
Descriptor | Tumor necrosis factor ligand superfamily member 10, Tumor necrosis factor receptor superfamily member 10A, ZINC ION, ... (5 entities in total) |
Functional Keywords | apoptosis, binding and specificity, ligand-receptor complex, tnf receptor family |
Biological source | Homo sapiens (Human) More |
Cellular location | Membrane ; Single-pass type II membrane protein : P50591 Membrane; Single-pass type I membrane protein: O00220 |
Total number of polymer chains | 6 |
Total formula weight | 94304.86 |
Authors | Sheriff, S. (deposition date: 2015-07-13, release date: 2017-01-18, Last modification date: 2023-09-27) |
Primary citation | Ramamurthy, V.,Yamniuk, A.P.,Lawrence, E.J.,Yong, W.,Schneeweis, L.A.,Cheng, L.,Murdock, M.,Corbett, M.J.,Doyle, M.L.,Sheriff, S. The structure of the death receptor 4-TNF-related apoptosis-inducing ligand (DR4-TRAIL) complex. Acta Crystallogr F Struct Biol Commun, 71:1273-1281, 2015 Cited by PubMed: 26457518DOI: 10.1107/S2053230X15016416 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
Download full validation report