6CU0
Crystal structure of 4-1BBL/4-1BB (C121S) complex in P21 space group
Summary for 6CU0
| Entry DOI | 10.2210/pdb6cu0/pdb |
| Descriptor | Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
| Functional Keywords | complex, cytokine |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 12 |
| Total formula weight | 194630.72 |
| Authors | Aruna, B.,Zajonc, D.M.,Doukov, T. (deposition date: 2018-03-23, release date: 2018-05-09, Last modification date: 2023-10-04) |
| Primary citation | Bitra, A.,Doukov, T.,Croft, M.,Zajonc, D.M. Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier. J. Biol. Chem., 293:9958-9969, 2018 Cited by PubMed: 29720398DOI: 10.1074/jbc.RA118.003176 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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