2RJK

Crystal Structure of Human TL1A Extracellular Domain C95S Mutant

Summary for 2RJK

Entry DOI	10.2210/pdb2rjk/pdb
Related	2QE3 2RJL
Descriptor	TNF superfamily ligand TL1A (2 entities in total)
Functional Keywords	tl1a, tnfsf, cytokine, mutant, membrane, transmembrane
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	20893.68
Authors	Zhan, C.,Yan, Q.,Patskovsky, Y.,Shi, W.,Ramagopal, U.A.,Toro, R.,Bonanno, J.,Nathenson, S.G.,Almo, S.C. (deposition date: 2007-10-15, release date: 2008-08-26, Last modification date: 2023-08-30)
Primary citation	Zhan, C.,Yan, Q.,Patskovsky, Y.,Li, Z.,Toro, R.,Meyer, A.,Cheng, H.,Brenowitz, M.,Nathenson, S.G.,Almo, S.C. Biochemical and structural characterization of the human TL1A ectodomain. Biochemistry, 48:7636-7645, 2009 Cited by PubMed: 19522538 DOI: 10.1021/bi900031w PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation