3QD6

Crystal structure of the CD40 and CD154 (CD40L) complex

Summary for 3QD6

Entry DOI	10.2210/pdb3qd6/pdb
Descriptor	CD40 ligand, Tumor necrosis factor receptor superfamily member 5, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	immune regulator, receptor, cytokine-cytokine receptor complex, cytokine/cytokine receptor
Biological source	Homo sapiens (human) More
Total number of polymer chains	10
Total formula weight	176015.15
Authors	Lee, J.-O.,Kim, Y.J.,Song, D.H.,Kim, H.M.,Park, B.S. (deposition date: 2011-01-18, release date: 2011-02-02, Last modification date: 2023-11-01)
Primary citation	An, H.-J.,Kim, Y.J.,Song, D.H.,Park, B.S.,Kim, H.M.,Lee, J.D.,Paik, S.-G.,Lee, J.-O.,Lee, H. Crystallographic and mutational analysis of the CD40-CD154 complex and its implications for receptor activation J.Biol.Chem., 286:11226-11235, 2011 Cited by PubMed: 21285457 DOI: 10.1074/jbc.M110.208215 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation