3QD6
Crystal structure of the CD40 and CD154 (CD40L) complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | CD40 ligand | polymer | 149 | 16096.1 | 6 | UniProt (P29965) Pfam (PF00229) | Homo sapiens (human) | CD40-L |
| 2 | G, H, I, J (R, S, T, U) | Tumor necrosis factor receptor superfamily member 5 | polymer | 177 | 19527.8 | 4 | UniProt (P25942) Pfam (PF00020) | Homo sapiens (human) | CD40L receptor |
| 3 | K, L, M, N, O... (A, B, C, D, E...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) |
Sequence modifications
A, B, C, D, E, F: 116 - 261 (UniProt: P29965)
R, S, T, U: 21 - 190 (UniProt: P25942)
| PDB | External Database | Details |
|---|---|---|
| Ala 113 | - | expression tag |
| Asp 114 | - | expression tag |
| Pro 115 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 191 | - | expression tag |
| Gly 192 | - | expression tag |
| Arg 193 | - | expression tag |
| Leu 194 | - | expression tag |
| Val 195 | - | expression tag |
| Pro 196 | - | expression tag |
| Arg 197 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 174687.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1327.2 | |
| All* | Total formula weight | 176015.2 |
