PDB: 55616 件ウェブページステータス検索Chemie searchBIRD

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1H50	Structure of Pentaerythritol Tetranitrate Reductase and complexes 分子名称: ACETATE ION, FLAVIN MONONUCLEOTIDE, PENTAERYTHRITOL TETRANITRATE REDUCTASE 著者 Barna, T, Moody, P.C.E. 登録日 2001-05-17 公開日 2001-07-05 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of Pentaerythritol Tetranitrate Reductase: "Flipped" Binding Geometries for Steroid Substrates in Different Redox States of the Enzyme J.Mol.Biol., 310, 2001
1QXZ	Crystal structure of S. aureus methionine aminopeptidase in complex with a ketoheterocycle inhibitor 119 分子名称: (2S)-2-AMINO-4-(METHYLSULFANYL)-1-(1,3-THIAZOL-2-YL)BUTANE-1,1-DIOL, COBALT (II) ION, methionyl aminopeptidase 著者 Douangamath, A, Dale, G.E, D'Arcy, A, Oefner, C. 登録日 2003-09-09 公開日 2004-03-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Crystal structures of staphylococcusaureus methionine aminopeptidase complexed with keto heterocycle and aminoketone inhibitors reveal the formation of a tetrahedral intermediate. J.Med.Chem., 47, 2004
1QXW	Crystal structure of Staphyloccocus aureus in complex with an aminoketone inhibitor 54135. 分子名称: (3S)-3-AMINO-1-(CYCLOPROPYLAMINO)HEPTANE-2,2-DIOL, ACETATE ION, COBALT (II) ION, ... 著者 Douangamath, A, Dale, G.E, D'Arcy, A, Oefner, C. 登録日 2003-09-09 公開日 2004-03-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Crystal structures of staphylococcusaureus methionine aminopeptidase complexed with keto heterocycle and aminoketone inhibitors reveal the formation of a tetrahedral intermediate. J.Med.Chem., 47, 2004
1QXY	Crystal structure of S. aureus methionine aminopeptidase in complex with a ketoheterocycle 618 分子名称: (2S)-2-AMINO-4-(METHYLSULFANYL)-1-PYRIDIN-2-YLBUTANE-1,1-DIOL, ACETATE ION, COBALT (II) ION, ... 著者 Douangamath, A, Dale, G.E, D'Arcy, A, Oefner, C. 登録日 2003-09-09 公開日 2004-03-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.04 Å) 主引用文献 Crystal structures of staphylococcusaureus methionine aminopeptidase complexed with keto heterocycle and aminoketone inhibitors reveal the formation of a tetrahedral intermediate. J.Med.Chem., 47, 2004
2WYR	3-D structure of PhTET1-12s, dodecamer in the asymmetric unit 分子名称: COBALT (II) ION, COBALT-ACTIVATED PEPTIDASE TET1 著者 Vellieux, F.M.D, Dura, M.A, Franzetti, B. 登録日 2009-11-20 公開日 2010-12-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.245 Å) 主引用文献 Structure of Phtet1-12S, Dodecamer in the Asymmetric Unit To be Published
2UZS	A transforming mutation in the pleckstrin homology domain of AKT1 in cancer (AKT1-PH_E17K) 分子名称: INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, RAC-alpha serine/threonine-protein kinase 著者 Carpten, J.D, Faber, A.L, Horn, C, Donoho, G.P, Briggs, S.L, Robbins, C.M, Hostetter, G, Boguslawski, S, Moses, T.Y, Savage, S, Uhlik, M, Lin, A, Du, J, Qian, Y.W, Zeckner, D.J, Tucker-Kellogg, G, Touchman, J, Patel, K, Mousses, S, Bittner, M, Schevitz, R, Lai, M.H, Blanchard, K.L, Thomas, J.E. 登録日 2007-05-01 公開日 2007-07-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 A transforming mutation in the pleckstrin homology domain of AKT1 in cancer. Nature, 448, 2007
2R2L	Structure of Farnesyl Protein Transferase bound to PB-93 分子名称: FARNESYL DIPHOSPHATE, Farnesyltransferase subunit alpha, Farnesyltransferase subunit beta, ... 著者 Strickland, C.O, Voorhis, W. 登録日 2007-08-27 公開日 2008-03-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Efficacy, pharmacokinetics, and metabolism of tetrahydroquinoline inhibitors of Plasmodium falciparum protein farnesyltransferase. Antimicrob.Agents Chemother., 51, 2007
7X5C	Solution structure of Tetrahymena p75OB1-p50PBM 分子名称: Telomerase associated protein p50PBM, Telomerase-associated protein p75OB1 著者 Wu, B, Tang, T, Xue, H.J, Wu, J, Lei, M. 登録日 2022-03-04 公開日 2022-10-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Association of the CST complex and p50 in Tetrahymena is crucial for telomere maintenance Structure, 2022
8TWF	Crystal structure of tetracycline destructase Tet(56-3) 分子名称: 6-hydroxynicotinate 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE 著者 Kumar, H, Tang, W.K, Tolia, N. 登録日 2023-08-21 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes. Commun Biol, 7, 2024
6R8N	STRUCTURE DETERMINATION OF THE TETRAHEDRAL AMINOPEPTIDASE TET2 FROM P. HORIKOSHII BY USE OF COMBINED SOLID-STATE NMR, SOLUTION-STATE NMR AND EM DATA 4.1 A, FOLLOWED BY REAL_SPACE_REFINEMENT AT 4.1 A 分子名称: Tetrahedral aminopeptidase, ZINC ION 著者 Colletier, J.-P, Gauto, D, Estrozi, L, Favier, A, Effantin, G, Schoehn, G, Boisbouvier, J, Schanda, P. 登録日 2019-04-02 公開日 2019-08-14 最終更新日 2023-09-13 実験手法 ELECTRON MICROSCOPY (4.1 Å), SOLUTION NMR 主引用文献 Integrated NMR and cryo-EM atomic-resolution structure determination of a half-megadalton enzyme complex. Nat Commun, 10, 2019
6F3K	Combined solid-state NMR, solution-state NMR and EM data for structure determination of the tetrahedral aminopeptidase TET2 from P. horikoshii 分子名称: Tetrahedral aminopeptidase, ZINC ION 著者 Gauto, D.F, Estrozi, L.F, Schwieters, C.D, Effantin, G, Macek, P, Sounier, R, Kerfah, R, Sivertsen, A.C, Colletier, J.P, Boisbouvier, J, Schoehn, G, Favier, A, Schanda, P. 登録日 2017-11-28 公開日 2018-03-14 最終更新日 2023-09-13 実験手法 ELECTRON MICROSCOPY (4.1 Å), SOLID-STATE NMR, SOLUTION NMR 主引用文献 Integrated NMR and cryo-EM atomic-resolution structure determination of a half-megadalton enzyme complex. Nat Commun, 10, 2019
8TWG	Crystal structure of tetracycline destructase Tet(56-2) 分子名称: 6-hydroxynicotinate 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE 著者 Kumar, H, Tang, W.K, Tolia, N. 登録日 2023-08-21 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes. Commun Biol, 7, 2024
7YSK	Crystal structure of D-Cysteine desulfhydrase from Pectobacterium atrosepticum 分子名称: D-Cysteine desulfhydrase 著者 Zhang, X, Wang, L, Xu, X, Xing, X, Zhou, J. 登録日 2022-08-12 公開日 2022-12-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Characterization and structural basis of D-cysteine desulfhydrase from Pectobacterium atrosepticum Tetrahedron, 2022
7YSL	Crystal structure of D-Cysteine desulfhydrase with a trapped PLP-pyruvate geminal diamine 分子名称: 1,2-ETHANEDIOL, D-Cysteine desulfhydrase, FORMIC ACID 著者 Zhang, X, Wang, L, Xu, X, Xing, X, Zhou, J. 登録日 2022-08-12 公開日 2022-12-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Characterization and structural basis of D-cysteine desulfhydrase from Pectobacterium atrosepticum Tetrahedron, 2022
4PY4	Crystal structure of human poly(ADP-ribose) polymerase 14, catalytic domain in complex with an inhibitor XL2 分子名称: 2-({4-[(1R)-1-(dimethylamino)ethyl]phenyl}amino)-6-fluoro-1,3-benzothiazole-4-carboxamide, Poly [ADP-ribose] polymerase 14 著者 Li, J, Xu, Y. 登録日 2014-03-26 公開日 2015-04-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Palladium-catalyzed N-arylation of 2-aminobenzothiazole-4-carboxylates/carboxamides: facile synthesis of PARP14 inhibitors Tetrahedron, 70, 2017
4MC6	HIV protease in complex with SA499 分子名称: 1,2-ETHANEDIOL, 1-tert-butyl-3-{(2S,3R)-4-[(4R)-7-fluoro-1,1-dioxido-4-(propan-2-yl)-4,5-dihydro-1,2-benzothiazepin-2(3H)-yl]-3-hydroxy-1-phenylbutan-2-yl}urea, CHLORIDE ION, ... 著者 Ganguly, A.K, Alluri, S.S, Wang, C, Antropow, A, White, A, Caroccia, D, Biswas, D, Kang, E, Zhang, L, Carroll, S.S, Burlein, C, Munshi, V, Orth, P, Strickland, C. 登録日 2013-08-21 公開日 2014-04-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 Structural Optimization of Cyclic Sulfonamide based Novel HIV-1 Protease Inhibitors to Pico Molar Affinities guided by X-ray Crystallographic Analysis Tetrahedron, 2014
2PAH	TETRAMERIC HUMAN PHENYLALANINE HYDROXYLASE 分子名称: FE (III) ION, PROTEIN (PHENYLALANINE HYDROXYLASE) 著者 Stevens, R.C, Fusetti, F, Erlandsen, H. 登録日 1998-05-26 公開日 1999-10-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of tetrameric human phenylalanine hydroxylase and its implications for phenylketonuria. J.Biol.Chem., 273, 1998
1FIU	TETRAMERIC RESTRICTION ENDONUCLEASE NGOMIV IN COMPLEX WITH CLEAVED DNA 分子名称: ACETIC ACID, DNA (5'-D(*TP*GP*CP*G)-3'), DNA (5'-D(P*CP*CP*GP*GP*CP*GP*C)-3'), ... 著者 Deibert, M, Grazulis, S, Sasnauskas, G, Siksnys, V, Huber, R. 登録日 2000-08-07 公開日 2001-02-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of the tetrameric restriction endonuclease NgoMIV in complex with cleaved DNA. Nat.Struct.Biol., 7, 2000
1RSO	Hetero-tetrameric L27 (Lin-2, Lin-7) domain complexes as organization platforms of supra-molecular assemblies 分子名称: Peripheral plasma membrane protein CASK, Presynaptic protein SAP97 著者 Feng, W, Long, J.-F, Fan, J.-S, Suetake, T, Zhang, M. 登録日 2003-12-09 公開日 2004-05-04 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 The tetrameric L27 domain complex as an organization platform for supramolecular assemblies NAT.STRUCT.MOL.BIOL., 11, 2004
3KVT	TETRAMERIZATION DOMAIN FROM AKV3.1 (SHAW-SUBFAMILY) VOLTAGE-GATED POTASSIUM CHANNEL 分子名称: POTASSIUM CHANNEL PROTEIN SHAW, ZINC ION 著者 Bixby, K.A, Nanao, M.H, Shen, N.V, Kreusch, A, Bellamy, H, Pfaffinger, P.J, Choe, S. 登録日 1998-09-25 公開日 1999-01-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels. Nat.Struct.Biol., 6, 1999
7LHK	High-Resolution Crystal Structure of a Lipin/Pah Phosphatidic Acid Phosphatase 分子名称: CACODYLATE ION, Nuclear elongation and deformation protein 著者 Khayyo, V.I, Airola, M.V. 登録日 2021-01-25 公開日 2022-02-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 High-resolution structure of phosphatidic acid phosphohydrolase from Tetrahymena thermophila To be published
6D6V	CryoEM structure of Tetrahymena telomerase with telomeric DNA at 4.8 Angstrom resolution 分子名称: DNA (5'-D(P*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*G)-3'), RNA (159-MER), Telomerase associated protein p65, ... 著者 Jiang, J, Wang, Y, Susac, L, Chan, H, Basu, R, Zhou, Z.H, Feigon, J. 登録日 2018-04-22 公開日 2018-05-30 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Structure of Telomerase with Telomeric DNA. Cell, 173, 2018
6QMH	Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis in complex with 3-(1H-indol-3-yl)propanoic acid at 1.6A resolution. 分子名称: 5-[3-(1~{H}-indol-3-yl)propoxy]-1-phenyl-pyrazole-4-carboxylic acid, Phosphopantetheine adenylyltransferase 著者 Blaszczyk, M, Blundell, T.L. 登録日 2019-02-07 公開日 2020-02-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.837 Å) 主引用文献 Fragment linking applied to the discovery of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase inhibitors To Be Published
6QMI	Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis in complex with 3-(1H-indol-1-yl)propanoic acid at 1.7A resolution. 分子名称: 5-methyl-1-phenyl-pyrazole-4-carboxylic acid, Phosphopantetheine adenylyltransferase 著者 Blaszczyk, M, Blundell, T.L. 登録日 2019-02-07 公開日 2020-02-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.781 Å) 主引用文献 Fragment linking applied to the discovery of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase inhibitors To Be Published
6QMF	Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis in complex with 5-[3-(1H-indol-3-yl)propoxy]-1-phenyl-1H-pyrazole-4-carboxylic acid at 1.8A resolution. 分子名称: 3-indol-1-ylpropanoic acid, DIMETHYL SULFOXIDE, Phosphopantetheine adenylyltransferase 著者 Blaszczyk, M, Blundell, T.L. 登録日 2019-02-07 公開日 2020-02-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.771 Å) 主引用文献 Fragment linking applied to the discovery of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase inhibitors To Be Published

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