6QMH
Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis in complex with 3-(1H-indol-3-yl)propanoic acid at 1.6A resolution.
Replaces: 6G7TSummary for 6QMH
Entry DOI | 10.2210/pdb6qmh/pdb |
Descriptor | Phosphopantetheine adenylyltransferase, 5-[3-(1~{H}-indol-3-yl)propoxy]-1-phenyl-pyrazole-4-carboxylic acid (3 entities in total) |
Functional Keywords | coad, ppat, transferase, complex |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 18153.78 |
Authors | Blaszczyk, M.,Blundell, T.L. (deposition date: 2019-02-07, release date: 2020-02-26, Last modification date: 2024-01-24) |
Primary citation | Blaszczyk, M.,El Bakali, J.,Boland, J.A.,Spry, C.,Dias, M.,Blundell, T.L.,Abel, C. Fragment linking applied to the discovery of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase inhibitors To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.837 Å) |
Structure validation
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