1QXY

Crystal structure of S. aureus methionine aminopeptidase in complex with a ketoheterocycle 618

Summary for 1QXY

Entry DOI	10.2210/pdb1qxy/pdb
Related	1QXW 1QXZ
Descriptor	methionyl aminopeptidase, COBALT (II) ION, ACETATE ION, ... (5 entities in total)
Functional Keywords	pita bread fold, hydrolase
Biological source	Staphylococcus aureus
Total number of polymer chains	1
Total formula weight	27999.41
Authors	Douangamath, A.,Dale, G.E.,D'Arcy, A.,Oefner, C. (deposition date: 2003-09-09, release date: 2004-03-16, Last modification date: 2024-02-14)
Primary citation	Douangamath, A.,Dale, G.E.,D'Arcy, A.,Almstetter, M.,Eckl, R.,Frutos-Hoener, A.,Henkel, B.,Illgen, K.,Nerdinger, S.,Schulz, H.,MacSweeney, A.,Thormann, M.,Treml, A.,Pierau, S.,Wadman, S.,Oefner, C. Crystal structures of staphylococcusaureus methionine aminopeptidase complexed with keto heterocycle and aminoketone inhibitors reveal the formation of a tetrahedral intermediate. J.Med.Chem., 47:1325-1328, 2004 Cited by PubMed: 14998322 DOI: 10.1021/jm034188j PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.04 Å)

Structure validation