PDB: 35463 件ウェブページステータス検索Chemie searchBIRD

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2X3V	Structure of The F-BAR Domain of Mouse Syndapin I 分子名称: PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 1 著者 Ma, Q, Rao, Y, Vahedi-Faridi, A, Saenger, W, Haucke, V. 登録日 2010-01-27 公開日 2010-04-07 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Molecular Basis for SH3 Domain Regulation of F-Bar-Mediated Membrane Deformation. Proc.Natl.Acad.Sci.USA, 107, 2010
4BYF	Crystal structure of human Myosin 1c in complex with calmodulin in the pre-power stroke state 分子名称: ADP ORTHOVANADATE, CALMODULIN, MAGNESIUM ION, ... 著者 Munnich, S, Taft, M.H, Pathan-Chhatbar, S, Manstein, D.J. 登録日 2013-07-19 公開日 2014-03-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Crystal Structure of Human Myosin 1C-the Motor in Glut4 Exocytosis: Implications for Ca(2+) Regulation and 14-3-3 Binding. J.Mol.Biol., 426, 2014
6MDM	The 20S supercomplex engaging the SNAP-25 N-terminus (class 1) 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Alpha-soluble NSF attachment protein, ... 著者 White, K.I, Zhao, M, Brunger, A.T. 登録日 2018-09-04 公開日 2018-09-19 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structural principles of SNARE complex recognition by the AAA+ protein NSF. Elife, 7, 2018
2Q91	Structure of the Ca2+-Bound Activated Form of the S100A4 Metastasis Factor 分子名称: CALCIUM ION, S100A4 Metastasis Factor 著者 Malashkevich, V.N, Knight, D, Ramagopal, U.A, Almo, S.C, Bresnick, A.R. 登録日 2007-06-12 公開日 2008-02-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Structure of Ca(2+)-Bound S100A4 and Its Interaction with Peptides Derived from Nonmuscle Myosin-IIA. Biochemistry, 47, 2008
4CC4	Complex of InlC of Listeria monocytogenes and human Tuba C-terminal SH3 domain 分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, CHLORIDE ION, DYNAMIN-BINDING PROTEIN, ... 著者 Polle, L, Rigano, L, Julian, R, Ireton, K, Schubert, W.-D. 登録日 2013-10-17 公開日 2013-10-30 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Details of Human Tuba Recruitment by Inlc of Listeria Monocytogenes Elucidate Bacterial Cell-Cell Spreading. Structure, 22, 2014
5TKP	Crystal structure of FBP aldolase from Toxoplasma gondii, equilibrium Schiff base FBP complex 分子名称: 1,6-di-O-phosphono-D-fructose, Fructose-bisphosphate aldolase 著者 Heron, P.W, Sygusch, J. 登録日 2016-10-07 公開日 2017-10-04 最終更新日 2020-01-08 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Isomer activation controls stereospecificity of class I fructose-1,6-bisphosphate aldolases. J. Biol. Chem., 292, 2017
5XJT	Crystal Structure of the Gemin2-binding domain of SMN, Gemin2 in Complex with SmD1(1-82)/D2.R61A/F/E/G from Human 分子名称: Gem-associated protein 2, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ... 著者 Yi, H, Zhang, R. 登録日 2017-05-04 公開日 2018-07-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 Structures of 7S mutant complexes To Be Published
5TLZ	Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor naphthalene 2,6-bisphosphate 分子名称: Fructose-bisphosphate aldolase A, GLYCEROL, naphthalene-2,6-diyl bis[dihydrogen (phosphate)] 著者 Heron, P.W, Sygusch, J. 登録日 2016-10-12 公開日 2017-10-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase. J.Med.Chem., 61, 2018
5TB5	Crystal structure of full-length farnesylated and methylated KRAS4b in complex with PDE-delta (crystal form I - with partially disordered hypervariable region) 分子名称: 1,2-ETHANEDIOL, FARNESYL, GTPase KRas, ... 著者 Dharmaiah, S, Tran, T.H, Simanshu, D.K. 登録日 2016-09-11 公開日 2016-11-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis of recognition of farnesylated and methylated KRAS4b by PDE delta. Proc.Natl.Acad.Sci.USA, 113, 2016
5TJS	Crystal structure of FBP aldolase from Toxoplasma gondii, native form 分子名称: Fructose-bisphosphate aldolase, GLYCEROL 著者 Heron, P.W, Sygusch, J. 登録日 2016-10-05 公開日 2017-10-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Isomer activation controls stereospecificity of class I fructose-1,6-bisphosphate aldolases. J. Biol. Chem., 292, 2017
5TK3	Crystal structure of FBP aldolase from Toxoplasma gondii, burst-phase ternary complex 分子名称: 1,3-DIHYDROXYACETONEPHOSPHATE, Fructose-bisphosphate aldolase, GLYCERALDEHYDE-3-PHOSPHATE, ... 著者 Heron, P.W, Sygusch, J. 登録日 2016-10-06 公開日 2017-10-04 最終更新日 2020-01-08 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Isomer activation controls stereospecificity of class I fructose-1,6-bisphosphate aldolases. J. Biol. Chem., 292, 2017
5TKN	Crystal structure of FBP aldolase from Toxoplasma gondii, Schiff base FBP complex 分子名称: 1,6-di-O-phosphono-D-fructose, Fructose-bisphosphate aldolase 著者 Heron, P.W, Sygusch, J. 登録日 2016-10-07 公開日 2017-10-04 最終更新日 2020-01-08 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Isomer activation controls stereospecificity of class I fructose-1,6-bisphosphate aldolases. J. Biol. Chem., 292, 2017
5XUQ	Crystal structure of VDR-LBD complexed with an antagonist, 2-methylidene-19,26,27-trinor-22-(S)-butyl-1-hydroxy-25-oxo-25-(1H-pyrrol-2-yl)- vitamin D3 分子名称: (4~{S})-4-[(1~{R})-1-[(1~{R},3~{a}~{S},4~{E},7~{a}~{R})-7~{a}-methyl-4-[2-[(3~{R},5~{R})-4-methylidene-3,5-bis(oxidanyl)cyclohexylidene]ethylidene]-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-1-yl]ethyl]-1-(1~{H}-pyrrol-2-yl)octan-1-one, Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor 著者 Kato, A, Itoh, T, Yamamoto, K. 登録日 2017-06-24 公開日 2018-06-27 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Discovery of Potent Vitamin D Receptor Antagonist To Be Published
5TLW	Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor 1-phosphate-benzene 4-bisphosphonate 分子名称: Fructose-bisphosphate aldolase A, GLYCEROL, {[4-(phosphonooxy)phenyl]methylene}bis(phosphonic acid) 著者 Heron, P.W, Sygusch, J. 登録日 2016-10-12 公開日 2017-10-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase. J.Med.Chem., 61, 2018
6KC4	Crystal structure of human Fer SH2 domain bound to a phosphopeptide (DEpYENVD) 分子名称: Tyrosine-protein kinase Fer, phosphopeptide (EDpYENVD) 著者 Matsuura, Y. 登録日 2019-06-27 公開日 2019-09-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 High-resolution structural analysis shows how different crystallographic environments can induce alternative modes of binding of a phosphotyrosine peptide to the SH2 domain of Fer tyrosine kinase. Protein Sci., 28, 2019
5XBL	Structure of nuclease in complex with associated protein 分子名称: Associated protein, CRISPR-associated endonuclease Cas9/Csn1, RNA (98-MER) 著者 Dong, D, Guo, M, Wang, S, Zhu, Y, Huang, Z. 登録日 2017-03-20 公開日 2017-06-14 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (3.052 Å) 主引用文献 Structural basis of CRISPR-SpyCas9 inhibition by an anti-CRISPR protein Nature, 546, 2017
2P2T	Crystal structure of dynein light chain LC8 bound to residues 123-138 of intermediate chain IC74 分子名称: ACETATE ION, Dynein intermediate chain peptide, Dynein light chain 1, ... 著者 Benison, G, Karplus, P.A, Barbar, E. 登録日 2007-03-07 公開日 2008-01-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure and dynamics of LC8 complexes with KXTQT-motif peptides: swallow and dynein intermediate chain compete for a common site. J.Mol.Biol., 371, 2007
2MSE	NMR data-driven model of GTPase KRas-GNP:ARafRBD complex tethered to a lipid-bilayer nanodisc 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... 著者 Mazhab-Jafari, M, Stathopoulos, P, Marshall, C, Ikura, M. 登録日 2014-07-29 公開日 2015-06-03 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site. Proc.Natl.Acad.Sci.USA, 112, 2015
2X3W	structure of mouse syndapin I (crystal form 2) 分子名称: PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 1 著者 Ma, Q, Rao, Y, Saenger, W, Haucke, V. 登録日 2010-01-28 公開日 2010-04-07 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Molecular Basis for SH3 Domain Regulation of F-Bar-Mediated Membrane Deformation. Proc.Natl.Acad.Sci.USA, 107, 2010
6M6X	Oridonin in complex with CRM1#-Ran-RanBP1 分子名称: (1beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14R,16beta)-1,6,7,14-tetrahydroxy-7,20-epoxykauran-15-one, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Sun, Q, Lei, Y. 登録日 2020-03-16 公開日 2021-03-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 Novel Mechanistic Observations and NES-Binding Groove Features Revealed by the CRM1 Inhibitors Plumbagin and Oridonin. J.Nat.Prod., 84, 2021
6LQ9	S109 in complex with CRM1-Ran-RanBP1 分子名称: (3~{R},4~{S})-1-[[6-chloranyl-5-(trifluoromethyl)pyridin-2-yl]amino]-3,4-dimethyl-pyrrolidine-2,5-dione, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Lei, Y. 登録日 2020-01-13 公開日 2021-06-23 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure-Guided Design of the First Noncovalent Small-Molecule Inhibitor of CRM1. J.Med.Chem., 64, 2021
5TKL	Crystal structure of FBP aldolase from Toxoplasma gondii, condensation intermediate 分子名称: 1,3-DIHYDROXYACETONEPHOSPHATE, 1,6-di-O-phosphono-D-fructose, Fructose-bisphosphate aldolase, ... 著者 Heron, P.W, Sygusch, J. 登録日 2016-10-06 公開日 2017-10-04 最終更新日 2020-01-08 実験手法 X-RAY DIFFRACTION (1.751 Å) 主引用文献 Isomer activation controls stereospecificity of class I fructose-1,6-bisphosphate aldolases. J. Biol. Chem., 292, 2017
6M60	Plumbagin in complex with CRM1#-Ran-RanBP1 分子名称: (2~{R})-2-methyl-5-oxidanyl-2,3-dihydronaphthalene-1,4-dione, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Sun, Q, Lei, Y. 登録日 2020-03-12 公開日 2021-06-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Novel Mechanistic Observations and NES-Binding Groove Features Revealed by the CRM1 Inhibitors Plumbagin and Oridonin. J.Nat.Prod., 84, 2021
5TLH	Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor 2-naphthol 6-bisphosphonate 分子名称: Fructose-bisphosphate aldolase A, GLYCEROL, METHYLENEDIPHOSPHONIC ACID, ... 著者 Heron, P.W, Sygusch, J. 登録日 2016-10-11 公開日 2017-10-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.204 Å) 主引用文献 Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase. J.Med.Chem., 61, 2018
2MSC	NMR data-driven model of GTPase KRas-GDP tethered to a lipid-bilayer nanodisc 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... 著者 Mazhab-Jafari, M, Stathopoulos, P, Marshall, C, Ikura, M. 登録日 2014-07-29 公開日 2015-06-03 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site. Proc.Natl.Acad.Sci.USA, 112, 2015

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