6KC4

Crystal structure of human Fer SH2 domain bound to a phosphopeptide (DEpYENVD)

Summary for 6KC4

Entry DOI	10.2210/pdb6kc4/pdb
Descriptor	Tyrosine-protein kinase Fer, phosphopeptide (EDpYENVD) (3 entities in total)
Functional Keywords	sh2 domain, signaling protein, transferase-signaling protein complex, transferase/signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	12
Total formula weight	76236.90
Authors	Matsuura, Y. (deposition date: 2019-06-27, release date: 2019-09-04, Last modification date: 2023-11-22)
Primary citation	Matsuura, Y. High-resolution structural analysis shows how different crystallographic environments can induce alternative modes of binding of a phosphotyrosine peptide to the SH2 domain of Fer tyrosine kinase. Protein Sci., 28:2011-2019, 2019 Cited by PubMed: 31441171 DOI: 10.1002/pro.3713 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.37 Å)

Structure validation