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6KC4

Crystal structure of human Fer SH2 domain bound to a phosphopeptide (DEpYENVD)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G, I...
(A, C, E, G, I...)
Tyrosine-protein kinase Ferpolymer10211743.36UniProt (P16591)
Pfam (PF00017)
Homo sapiens (Human)Feline encephalitis virus-related kinase FER,Fujinami poultry sarcoma/Feline sarcoma-related protein Fer,Proto-oncogene c-Fer,Tyrosine kinase 3,p94-Fer
2B, D, F, H, J...
(B, D, F, H, J...)
phosphopeptide (EDpYENVD)polymer7962.86synthetic construct
3M, N, O, P, Q...
(A, B, C, D, E...)
waterwater18.01075Chemie (HOH)
Sequence modifications
A, C, E, G, I, K: 453 - 552 (UniProt: P16591)
PDBExternal DatabaseDetails
Gly 451-expression tag
Ser 452-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight76236.9
All*Total formula weight76236.9
*Water molecules are not included.

242500

PDB entries from 2025-10-01

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