5TLZ
Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor naphthalene 2,6-bisphosphate
Summary for 5TLZ
Entry DOI | 10.2210/pdb5tlz/pdb |
Related | 5TLE 5TLH 5TLW |
Descriptor | Fructose-bisphosphate aldolase A, naphthalene-2,6-diyl bis[dihydrogen (phosphate)], GLYCEROL, ... (4 entities in total) |
Functional Keywords | inhibitor, complex, aldolase, lyase, lyase-inhibitor complex, lyase/inhibitor |
Biological source | Oryctolagus cuniculus (Rabbit) |
Total number of polymer chains | 4 |
Total formula weight | 158519.39 |
Authors | Heron, P.W.,Sygusch, J. (deposition date: 2016-10-12, release date: 2017-10-25, Last modification date: 2023-10-18) |
Primary citation | Heron, P.W.,Abellan-Flos, M.,Salmon, L.,Sygusch, J. Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase. J.Med.Chem., 61:10558-10572, 2018 Cited by PubMed: 30418024DOI: 10.1021/acs.jmedchem.8b01000 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.97 Å) |
Structure validation
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