5TLZ

Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor naphthalene 2,6-bisphosphate

Summary for 5TLZ

Entry DOI	10.2210/pdb5tlz/pdb
Related	5TLE 5TLH 5TLW
Descriptor	Fructose-bisphosphate aldolase A, naphthalene-2,6-diyl bis[dihydrogen (phosphate)], GLYCEROL, ... (4 entities in total)
Functional Keywords	inhibitor, complex, aldolase, lyase, lyase-inhibitor complex, lyase/inhibitor
Biological source	Oryctolagus cuniculus (Rabbit)
Total number of polymer chains	4
Total formula weight	158519.39
Authors	Heron, P.W.,Sygusch, J. (deposition date: 2016-10-12, release date: 2017-10-25, Last modification date: 2023-10-18)
Primary citation	Heron, P.W.,Abellan-Flos, M.,Salmon, L.,Sygusch, J. Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase. J.Med.Chem., 61:10558-10572, 2018 Cited by PubMed: 30418024 DOI: 10.1021/acs.jmedchem.8b01000 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.97 Å)

Structure validation