PDB: 82203 件ウェブページステータス検索Chemie searchBIRD

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1MKT	CARBOXYLIC ESTER HYDROLASE, 1.72 ANGSTROM TRIGONAL FORM OF THE BOVINE RECOMBINANT PLA2 ENZYME 分子名称: CALCIUM ION, PHOSPHOLIPASE A2 著者 Sundaralingam, M. 登録日 1997-09-06 公開日 1998-03-11 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 1.72 A resolution refinement of the trigonal form of bovine pancreatic phospholipase A2. Acta Crystallogr.,Sect.D, 54, 1998
3VM7	Structure of an Alpha-Amylase from Malbranchea cinnamomea 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-amylase, ... 著者 Zhou, P, Hu, S.Q, Zhou, Y, Han, P, Yang, S.Q, Jiang, Z.Q. 登録日 2011-12-09 公開日 2013-05-29 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 A Novel Multifunctional alpha-Amylase from the Thermophilic Fungus Malbranchea cinnamomea: Biochemical Characterization and Three-Dimensional Structure. Appl Biochem Biotechnol., 170, 2013
5AG4	CRYSTAL STRUCTURE OF LEISHMANIA MAJOR N-MYRISTOYLTRANSFERASE (NMT) WITH BOUND MYRISTOYL-COA AND A THIAZOLIDINONE LIGAND 分子名称: (2S)-3-(3-chlorophenyl)-2-(pyridin-2-yl)-1,3-thiazolidin-4-one, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, TETRADECANOYL-COA 著者 Robinson, D.A, Spinks, D, Smith, V.C, Thompson, S, Smith, A, Torrie, L.S, McElroy, S.P, Brand, S, Brenk, R, Frearson, J.A, Read, K.D, Wyatt, P.G, Gilbert, I.H. 登録日 2015-01-29 公開日 2015-10-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Development of Small-Molecule Trypanosoma Brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode. Chemmedchem, 10, 2015
5AGE	CRYSTAL STRUCTURE OF LEISHMANIA MAJOR N-MYRISTOYLTRANSFERASE (NMT) WITH BOUND MYRISTOYL-COA AND A BENZOMORPHOLINONE LIGAND 分子名称: 4-[(5-methyl-1,2-oxazol-3-yl)methyl]-7-[4-(1-methylpiperidin-4-yl)butyl]-2H-1,4-benzoxazin-3(4H)-one, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, TETRADECANOYL-COA 著者 Robinson, D.A, Spinks, D, Smith, V.C, Thompson, S, Smith, A, Torrie, L.S, McElroy, S.P, Brand, S, Brenk, R, Frearson, J.A, Read, K.D, Wyatt, P.G, Gilbert, I.H. 登録日 2015-01-29 公開日 2015-10-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Development of Small-Molecule Trypanosoma Brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode. Chemmedchem, 10, 2015
7NFT	Fujian capbinding domain in complex with Nb8208 分子名称: Nb8208, Polymerase basic protein 2, SULFATE ION 著者 Keown, J.R, Grimes, J.M, Fodor, E. 登録日 2021-02-07 公開日 2021-12-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.14 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
5AG7	CRYSTAL STRUCTURE OF LEISHMANIA MAJOR N-MYRISTOYLTRANSFERASE (NMT) WITH BOUND MYRISTOYL-COA AND A BENZOMORPHOLINE LIGAND 分子名称: GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, TETRADECANOYL-COA, ethyl (3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)acetate 著者 Robinson, D.A, Spinks, D, Smith, V.C, Thompson, S, Smith, A, Torrie, L.S, McElroy, S.P, Brand, S, Brenk, R, Frearson, J.A, Read, K.D, Wyatt, P.G, Gilbert, I.H. 登録日 2015-01-29 公開日 2015-10-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Development of Small-Molecule Trypanosoma Brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode. Chemmedchem, 10, 2015
1JV8	NMR Structure of BPTI Mutant G37A 分子名称: TRYPSIN INHIBITOR 著者 Battiste, J.L, Li, R, Woodward, C. 登録日 2001-08-28 公開日 2001-09-12 最終更新日 2021-10-27 実験手法 SOLUTION NMR 主引用文献 A highly destabilizing mutation, G37A, of the bovine pancreatic trypsin inhibitor retains the average native conformation but greatly increases local flexibility Biochemistry, 41, 2002
8H68	Crystal structure of Caenorhabditis elegans NMAD-1 in complex with NOG and Mg(II) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... 著者 Shi, Y, Ding, J, Yang, H. 登録日 2022-10-16 公開日 2023-02-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Caenorhabditis elegans NMAD-1 functions as a demethylase for actin. J Mol Cell Biol, 15, 2023
5FHN	Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with (S)-2-Amino-3-(5-(2-(3-methylbenzyl)-2H-tetrazol-5-yl)-3-hydroxyisoxazol-4-yl)propanoic acid at 1.6 A resolution 分子名称: (S)-2-Amino-3-(5-(2-(3-methylbenzyl)-2H-tetrazol-5-yl)-3-hydroxyisoxazol-4-yl)propanoic acid, 1,2-ETHANEDIOL, ACETATE ION, ... 著者 Frydenvang, K, Kastrup, J.S. 登録日 2015-12-22 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Tweaking Subtype Selectivity and Agonist Efficacy at (S)-2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) Receptors in a Small Series of BnTetAMPA Analogues. J.Med.Chem., 59, 2016
1GH4	Structure of the triple mutant (K56M, K120M, K121M) of phospholipase A2 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, PHOSPHOLIPASE A2 著者 Sekar, K, Velmurugan, D, Tsai, M.D. 登録日 2000-11-09 公開日 2001-05-09 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Observation of additional calcium ion in the crystal structure of the triple mutant K56,120,121M of bovine pancreatic phospholipase A2. J.Mol.Biol., 324, 2002
4WZI	Crystal structure of crosslink stabilized long-form PDE4B 分子名称: IODIDE ION, MAGNESIUM ION, SODIUM ION, ... 著者 Cedervall, P, Pandit, J. 登録日 2014-11-19 公開日 2015-03-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Engineered stabilization and structural analysis of the autoinhibited conformation of PDE4. Proc.Natl.Acad.Sci.USA, 112, 2015
5FQM	Last common ancestor of Gram Negative Bacteria (GNCA) Class A beta- lactamase 分子名称: GLYCEROL, GNCA BETA LACTAMASE, SULFATE ION 著者 Martinez Rodriguez, S, Gavira, J.A, Risso, V.A, Sanchez Ruiz, J.M. 登録日 2015-12-12 公開日 2017-01-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 De novo active sites for resurrected Precambrian enzymes. Nat Commun, 8, 2017
4YND	The Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2 分子名称: N-cyclohexyl-N~3~-[2-(3,4-dichlorophenyl)ethyl]-N-(2-{[(2R)-2-hydroxy-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-8-yl)ethyl]amino}ethyl)-beta-alaninamide, N-lysine methyltransferase SMYD2, S-ADENOSYLMETHIONINE, ... 著者 Sweis, R.F, Wang, Z, Algire, M, Arrowsmith, C.H, Brown, P.J, Chiang, G.C, Guo, J, Jakob, C.G, Kennedy, S, Li, F, Soni, N.B, Vedadi, M, Pappano, W.N. 登録日 2015-03-09 公開日 2015-05-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2. Acs Med.Chem.Lett., 6, 2015
5FQI	W229D and F290W mutant of the last common ancestor of Gram-negative bacteria (GNCA4) beta-lactamase class A 分子名称: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, DI(HYDROXYETHYL)ETHER, ... 著者 Gavira, J.A, Risso, V.A, Martinez-Rodriguez, S, Sanchez-Ruiz, J.M. 登録日 2015-12-11 公開日 2016-12-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 De novo active sites for resurrected Precambrian enzymes. Nat Commun, 8, 2017
5M1X	Crystal structure of S. cerevisiae Rfa1 N-OB domain mutant (K45E) 分子名称: Replication factor A protein 1 著者 Seeber, A, Hegnauer, A.M, Hustedt, N, Deshpande, I, Poli, J, Eglinger, J, Pasero, P, Gut, H, Shinohara, M, Hopfner, K.P, Shimada, K, Gasser, S.M. 登録日 2016-10-11 公開日 2016-12-07 最終更新日 2016-12-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 RPA Mediates Recruitment of MRX to Forks and Double-Strand Breaks to Hold Sister Chromatids Together. Mol. Cell, 64, 2016
7E2X	Apo serotonin 1A (5-HT1A) receptor-Gi protein complex 分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Xu, P, Huang, S, Zhang, H, Mao, C, Zhou, X.E, Shen, D.D, Jiang, Y, Zhang, Y, Xu, H.E. 登録日 2021-02-07 公開日 2021-04-14 最終更新日 2021-04-28 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural insights into the lipid and ligand regulation of serotonin receptors. Nature, 592, 2021
1JV9	NMR Structure of BPTI Mutant G37A 分子名称: TRYPSIN INHIBITOR 著者 Battiste, J.L, Li, R, Woodward, C. 登録日 2001-08-28 公開日 2001-09-12 最終更新日 2021-10-27 実験手法 SOLUTION NMR 主引用文献 A highly destabilizing mutation, G37A, of the bovine pancreatic trypsin inhibitor retains the average native conformation but greatly increases local flexibility Biochemistry, 41, 2002
7XTJ	Crystal structure of E88A mutant of GH3 beta-xylosidase from Aspergillus niger (AnBX) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Kaenying, W, Kongsaeree, P.T, Tagami, T. 登録日 2022-05-17 公開日 2023-03-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure and identification of amino acid residues for catalysis and binding of GH3 AnBX beta-xylosidase from Aspergillus niger. Appl.Microbiol.Biotechnol., 107, 2023
4WVM	Stonustoxin structure 分子名称: Stonustoxin subunit alpha, Stonustoxin subunit beta 著者 Ellisdon, A.M, Panjikar, S, Whisstock, J.C, McGowan, S. 登録日 2014-11-06 公開日 2015-12-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Stonefish toxin defines an ancient branch of the perforin-like superfamily. Proc.Natl.Acad.Sci.USA, 112, 2015
1OBR	CARBOXYPEPTIDASE T 分子名称: CALCIUM ION, CARBOXYPEPTIDASE T, SULFATE ION, ... 著者 Teplyakov, A, Polyakov, K, Obmolova, G, Osterman, A. 登録日 1996-06-22 公開日 1997-01-11 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of carboxypeptidase T from Thermoactinomyces vulgaris. Eur.J.Biochem., 208, 1992
1GP7	Acidic Phospholipase A2 from venom of Ophiophagus Hannah 分子名称: CALCIUM ION, PHOSPHOLIPASE A2 著者 Zhang, H, Lin, Z. 登録日 2001-10-30 公開日 2002-10-31 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of a Cardiotoxic Phospholipase A(2) from Ophiophagus Hannah with the "Pancreatic Loop" J.Struct.Biol., 138, 2002
8FTG	Biophysical and Structural Characterization of an Anti-Caffeine VHH Antibody 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Anti-Caffeine VHH Antibody, CAFFEINE, ... 著者 Horn, J.R, Smith, C.A, Sonneson, G.J, Walter, R. 登録日 2023-01-12 公開日 2023-06-07 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Molecular recognition requires dimerization of a VHH antibody. Mabs, 15, 2023
4X0F	Crystal structure of crosslink stabilized long-form PDE4B in complex with (R)-(-)-rolipram 分子名称: IODIDE ION, MAGNESIUM ION, ROLIPRAM, ... 著者 Cedervall, P, Pandit, J. 登録日 2014-11-21 公開日 2015-03-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.22 Å) 主引用文献 Engineered stabilization and structural analysis of the autoinhibited conformation of PDE4. Proc.Natl.Acad.Sci.USA, 112, 2015
8HJO	Crystal structure of glycosyltransferase SgUGT94-289-3 in complex with UDP state 2 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, URIDINE-5'-DIPHOSPHATE, ... 著者 Li, M, Zhang, S, Cui, S. 登録日 2022-11-23 公開日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Structural insights into the catalytic selectivity of SgUGT94-289-3 towards mogrosides To Be Published
7E2Y	Serotonin-bound Serotonin 1A (5-HT1A) receptor-Gi protein complex 分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Xu, P, Huang, S, Zhang, H, Mao, C, Zhou, X.E, Shen, D.D, Jiang, Y, Zhang, Y, Xu, H.E. 登録日 2021-02-07 公開日 2021-04-14 最終更新日 2021-04-28 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural insights into the lipid and ligand regulation of serotonin receptors. Nature, 592, 2021

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