Stonustoxin structure

Summary for 4WVM

DescriptorStonustoxin subunit alpha, Stonustoxin subunit beta (2 entities in total)
Functional Keywordsmacpf cdc, membrane attack complex, perforin cholesterol dependent, cytolysin, venom, pry, spry, thioredoxin focal adhesion targeting, toxin
Biological sourceSynanceia horrida (Estuarine stonefish)
Cellular locationSecreted Q98989 Q91453
Total number of polymer chains2
Total molecular weight159139.21
Ellisdon, A.M.,Panjikar, S.,Whisstock, J.C.,McGowan, S. (deposition date: 2014-11-06, release date: 2015-12-02, Last modification date: 2017-11-22)
Primary citation
Ellisdon, A.M.,Reboul, C.F.,Panjikar, S.,Huynh, K.,Oellig, C.A.,Winter, K.L.,Dunstone, M.A.,Hodgson, W.C.,Seymour, J.,Dearden, P.K.,Tweten, R.K.,Whisstock, J.C.,McGowan, S.
Stonefish toxin defines an ancient branch of the perforin-like superfamily.
Proc.Natl.Acad.Sci.USA, 112:15360-15365, 2015
PubMed: 26627714 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1507622112
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2578 0.2% 1.8% 0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-21