5FQI

W229D and F290W mutant of the last common ancestor of Gram-negative bacteria (GNCA4) beta-lactamase class A

Summary for 5FQI

Entry DOI	10.2210/pdb5fqi/pdb
Related	5FQJ 5FQK 5FQQ
Descriptor	GNCA4 LACTAMASE W229D AND F290W, GLYCEROL, 1,2-ETHANEDIOL, ... (8 entities in total)
Functional Keywords	hydrolase, precambrian, resurrected beta-lactamase, gnca4
Biological source	SYNTHETIC CONSTRUCT
Total number of polymer chains	1
Total formula weight	30376.20
Authors	Gavira, J.A.,Risso, V.A.,Martinez-Rodriguez, S.,Sanchez-Ruiz, J.M. (deposition date: 2015-12-11, release date: 2016-12-21, Last modification date: 2024-01-10)
Primary citation	Risso, V.A.,Martinez-Rodriguez, S.,Candel, A.M.,Kruger, D.M.,Pantoja-Uceda, D.,Ortega-Munoz, M.,Santoyo-Gonzalez, F.,Gaucher, E.A.,Kamerlin, S.C.L.,Bruix, M.,Gavira, J.A.,Sanchez-Ruiz, J.M. De novo active sites for resurrected Precambrian enzymes. Nat Commun, 8:16113-16113, 2017 Cited by PubMed: 28719578 DOI: 10.1038/ncomms16113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation