7E2X
Apo serotonin 1A (5-HT1A) receptor-Gi protein complex
Summary for 7E2X
Entry DOI | 10.2210/pdb7e2x/pdb |
EMDB information | 30971 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (8 entities in total) |
Functional Keywords | serotonin, 5-ht1a, gpcr, complex, g protein, gi, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 152089.90 |
Authors | Xu, P.,Huang, S.,Zhang, H.,Mao, C.,Zhou, X.E.,Shen, D.D.,Jiang, Y.,Zhang, Y.,Xu, H.E. (deposition date: 2021-02-07, release date: 2021-04-14, Last modification date: 2021-04-28) |
Primary citation | Xu, P.,Huang, S.,Zhang, H.,Mao, C.,Zhou, X.E.,Cheng, X.,Simon, I.A.,Shen, D.D.,Yen, H.Y.,Robinson, C.V.,Harpsoe, K.,Svensson, B.,Guo, J.,Jiang, H.,Gloriam, D.E.,Melcher, K.,Jiang, Y.,Zhang, Y.,Xu, H.E. Structural insights into the lipid and ligand regulation of serotonin receptors. Nature, 592:469-473, 2021 Cited by PubMed: 33762731DOI: 10.1038/s41586-021-03376-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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