8FTG

Biophysical and Structural Characterization of an Anti-Caffeine VHH Antibody

Summary for 8FTG

• Entry DOI: 10.2210/pdb8ftg/pdb
• Descriptor: Anti-Caffeine VHH Antibody, CAFFEINE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
• Functional Keywords: camelid antibody, nanobody, hapten recognition, vhh, dimerization, chemically-induced dimerization (cid) system, immune system
• Biological source: Lama glama
• Total number of polymer chains: 8
• Total formula weight: 106338.55

Authors

Horn, J.R.,Smith, C.A.,Sonneson, G.J.,Walter, R. (deposition date: 2023-01-12, release date: 2023-06-07)

• Primary citation: Smith, C.A.,Sonneson, G.J.,Hoey, R.J.,Hinerman, J.M.,Sheehy, K.,Walter, R.,Herr, A.B.,Horn, J.R.; Molecular recognition requires dimerization of a VHH antibody.; Mabs, 15:2215363-2215363, 2023; PubMed: 37243579; DOI: 10.1080/19420862.2023.2215363

Experimental method

X-RAY DIFFRACTION (1.13 Å)