8FTG
Biophysical and Structural Characterization of an Anti-Caffeine VHH Antibody
Summary for 8FTG
Entry DOI | 10.2210/pdb8ftg/pdb |
Descriptor | Anti-Caffeine VHH Antibody, CAFFEINE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total) |
Functional Keywords | camelid antibody, nanobody, hapten recognition, vhh, dimerization, chemically-induced dimerization (cid) system, immune system |
Biological source | Lama glama |
Total number of polymer chains | 8 |
Total formula weight | 106338.55 |
Authors | Horn, J.R.,Smith, C.A.,Sonneson, G.J.,Walter, R. (deposition date: 2023-01-12, release date: 2023-06-07, Last modification date: 2024-05-22) |
Primary citation | Smith, C.A.,Sonneson, G.J.,Hoey, R.J.,Hinerman, J.M.,Sheehy, K.,Walter, R.,Herr, A.B.,Horn, J.R. Molecular recognition requires dimerization of a VHH antibody. Mabs, 15:2215363-2215363, 2023 Cited by PubMed: 37243579DOI: 10.1080/19420862.2023.2215363 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.13 Å) |
Structure validation
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