PDB: 10970 件ウェブページステータス検索Chemie searchBIRD

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5DAT	Complex of yeast 80S ribosome with hypusine-containing eIF5A 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. 登録日 2015-08-20 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome To Be Published
6OF6	Crystal structure of tRNA^ Ala(GGC) bound to cognate 70S A-site 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Nguyen, H.A, Sunita, S, Dunham, C.M. 登録日 2019-03-28 公開日 2020-06-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Disruption of evolutionarily correlated tRNA elements impairs accurate decoding. Proc.Natl.Acad.Sci.USA, 117, 2020
6NSH	Modified ASL proline bound to Thermus thermophilus 70S (near-cognate) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Hoffer, E.D, Maehigashi, T, Subaramanian, S, Hong, S, Dunham, C.M. 登録日 2019-01-24 公開日 2020-10-14 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.397 Å) 主引用文献 Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing. Elife, 9, 2020
6O97	Crystal structure of the Thermus thermophilus 70S ribosome in complex with propylamycin and bound to mRNA and A-, P-, and E-site tRNAs at 2.75A resolution 分子名称: (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxyc yclohexyl 2-amino-2,4-dideoxy-4-propyl-alpha-D-glucopyranoside, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Matsushita, T, Sati, G.C, Kondasinghe, N, Pirrone, M.G, Kato, T, Waduge, P, Kumar, H.S, Sanchon, A.C, Dobosz-Bartoszek, M, Shcherbakov, D, Juhas, M, Hobbie, S.N, Schrepfer, T, Chow, C.S, Polikanov, Y.S, Schacht, J, Vasella, A, Bottger, E.C, Crich, D. 登録日 2019-03-13 公開日 2019-04-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Design, Multigram Synthesis, and in Vitro and in Vivo Evaluation of Propylamycin: A Semisynthetic 4,5-Deoxystreptamine Class Aminoglycoside for the Treatment of Drug-Resistant Enterobacteriaceae and Other Gram-Negative Pathogens. J. Am. Chem. Soc., 141, 2019
5D8B	Crystal structure of T. thermophilus ribosome containing a P-site wobble mismatch 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Svidritskiy, E, Korostelev, A.A. 登録日 2015-08-17 公開日 2015-10-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.63 Å) 主引用文献 Ribosome Structure Reveals Preservation of Active Sites in the Presence of a P-Site Wobble Mismatch. Structure, 23, 2015
6OPE	Crystal structure of tRNA^ Ala(GGC) U32-A38 bound to near-cognate 70S A site 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Nguyen, H.A, Sunita, S, Dunham, C.M. 登録日 2019-04-24 公開日 2020-06-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Disruption of evolutionarily correlated tRNA elements impairs accurate decoding. Proc.Natl.Acad.Sci.USA, 117, 2020
6OTR	Dimeric E.coli YoeB bound to Thermus thermophilus 70S post-cleavage (AAU) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Pavelich, I.P, Hoffer, E.D, Maehigashi, T, Dunham, C.M. 登録日 2019-05-03 公開日 2019-08-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.12 Å) 主引用文献 Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability. Nucleic Acids Res., 47, 2019
5DOX	Crystal structure of the Thermus thermophilus 70S ribosome in complex with Hygromycin-A at 3.1A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Polikanov, Y.S, Starosta, A.L, Juette, M.F, Altman, R.B, Terry, D.S, Lu, W, Burnett, B.J, Dinos, G, Reynolds, K, Blanchard, S.C, Steitz, T.A, Wilson, D.N. 登録日 2015-09-11 公開日 2015-12-30 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A. Mol.Cell, 58, 2015
5E7K	Structure of T. thermophilus 70S ribosome complex with mRNA and cognate tRNALys in the A-site 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Rozov, A, Demeshkina, N, Khusainov, I, Yusupov, M, Yusupova, G. 登録日 2015-10-12 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code. Nat Commun, 7, 2016
2CBJ	Structure of the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase in complex with PUGNAc 分子名称: CHLORIDE ION, HYALURONIDASE, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE 著者 Rao, F.V, Dorfmueller, H.C, Villa, F, Allwood, M, Eggleston, I.M, van Aalten, D.M.F. 登録日 2006-01-05 公開日 2006-02-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural insights into the mechanism and inhibition of eukaryotic O-GlcNAc hydrolysis. EMBO J., 25, 2006
2CBI	Structure of the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase 分子名称: CHLORIDE ION, GAMMA-BUTYROLACTONE, GLYCEROL, ... 著者 Rao, F.V, Dorfmueller, H.C, Villa, F, Allwood, M, Eggleston, I.M, van Aalten, D.M.F. 登録日 2006-01-04 公開日 2006-02-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural insights into the mechanism and inhibition of eukaryotic O-GlcNAc hydrolysis. EMBO J., 25, 2006
6HHQ	Crystal structure of compound C45 bound to the yeast 80S ribosome 分子名称: (3~{R})-3-[(1~{S})-2-[(1~{S},4~{a}~{R},6~{S},7~{S},8~{a}~{R})-6,7-bis(chloranyl)-5,5,8~{a}-trimethyl-2-methylidene-3,4,4~{a},6,7,8-hexahydro-1~{H}-naphthalen-1-yl]-1-oxidanyl-ethyl]pyrrolidine-2,5-dione, 18S ribosomal RNA, 25S ribosomal RNA, ... 著者 Pellegrino, S, Vanderwal, C.D, Yusupov, M. 登録日 2018-08-28 公開日 2019-02-20 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (3.10000038 Å) 主引用文献 Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome. Nucleic Acids Res., 47, 2019
6KGX	Structure of the phycobilisome from the red alga Porphyridium purpureum 分子名称: Allophycocyanin alpha subunit, Allophycocyanin beta 18 subunit, Allophycocyanin beta subunit, ... 著者 Sui, S.F, Ma, J.F, You, X, Sun, S. 登録日 2019-07-12 公開日 2019-12-11 最終更新日 2020-03-18 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis of energy transfer in Porphyridium purpureum phycobilisome. Nature, 579, 2020
5M1J	Nonstop ribosomal complex bound with Dom34 and Hbs1 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Hilal, T, Yamamoto, H, Loerke, J, Buerger, J, Mielke, T, Spahn, C.M.T. 登録日 2016-10-07 公開日 2017-01-18 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution. Nat Commun, 7, 2016
5NDK	Crystal structure of aminoglycoside TC007 co-crystallized with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. 登録日 2017-03-08 公開日 2017-12-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5MEI	Crystal structure of Agelastatin A bound to the 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 McClary, B, Zinshteyn, B, Meyer, M, Jouanneau, M, Pellegrino, S, Yusupova, G, Schuller, A, Reyes, J.C.P, Lu, J, Luo, C, Dang, Y, Romo, D, Yusupov, M, Green, R, Liu, J.O. 登録日 2016-11-15 公開日 2017-06-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A. Cell Chem Biol, 24, 2017
5NDG	Crystal structure of geneticin (G418) bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. 登録日 2017-03-08 公開日 2017-12-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NDJ	Crystal structure of aminoglycoside TC007 in complex with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA (soaking) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. 登録日 2017-03-08 公開日 2018-05-02 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NDW	Crystal structure of aminoglycoside TC007 bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. 登録日 2017-03-09 公開日 2017-12-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5LYB	Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCPmn 分子名称: 18S rRNA, 25S rRNA, 40S Ribosomal Protein S12, ... 著者 Melnikov, S, Mailliot, J. 登録日 2016-09-26 公開日 2016-11-23 最終更新日 2016-12-14 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Molecular insights into protein synthesis with proline residues. EMBO Rep., 17, 2016
5NDV	Crystal structure of Paromomycin bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. 登録日 2017-03-09 公開日 2017-12-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4V8G	Crystal structure of RMF bound to the 70S ribosome. 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... 著者 Polikanov, Y.S, Blaha, G.M, Steitz, T.A. 登録日 2011-12-11 公開日 2014-07-09 最終更新日 2014-12-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 How hibernation factors RMF, HPF, and YfiA turn off protein synthesis. Science, 336, 2012
4W2H	Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (co-crystallized), mRNA and deacylated tRNA in the P site 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... 著者 Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V. 登録日 2014-09-12 公開日 2014-10-15 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome. Mol.Cell, 56, 2014
4V9Q	Crystal Structure of Blasticidin S Bound to Thermus Thermophilus 70S Ribosome. 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Svidritskiy, E, Ling, C, Ermolenko, D.N, Korostelev, A.A. 登録日 2013-06-12 公開日 2014-07-09 最終更新日 2019-07-17 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome. Proc.Natl.Acad.Sci.USA, 110, 2013
4V5E	Insights into translational termination from the structure of RF2 bound to the ribosome 分子名称: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Weixlbaumer, A, Jin, H, Neubauer, C, Voorhees, R.M, Petry, S, Kelley, A.C, Ramakrishnan, V. 登録日 2009-04-30 公開日 2014-07-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Insights Into Translational Termination from the Structure of Rf2 Bound to the Ribosome. Science, 322, 2008

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