Crystal structure of RMF bound to the 70S ribosome.

This is a large structure.

Summary for 4V8G

Integrates3V22 3V23 3V24 3V25
Descriptor16S Ribosomal RNA, 30S Ribosomal Protein S2, 30S Ribosomal Protein S3, ... (56 entities in total)
Functional Keywordsribosome modulation factor, stress response, small subunit head movement, stationary phase, ribosome hibernation, ribosome
Biological sourceEscherichia coli
Cellular locationCytoplasm  P0AFW2
Total number of polymer chains106
Total molecular weight4384335.21
Polikanov, Y.S.,Blaha, G.M.,Steitz, T.A. (deposition date: 2011-12-11, release date: 2014-07-09, Last modification date: 2014-12-10)
Primary citation
Polikanov, Y.S.,Blaha, G.M.,Steitz, T.A.
How hibernation factors RMF, HPF, and YfiA turn off protein synthesis.
Science, 336:915-918, 2012
PubMed: 22605777 (PDB entries with the same primary citation)
DOI: 10.1126/science.1218538
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.253150.8%17.3%9.9%0.46MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4v8g
no rotation
Molmil generated image of 4v8g
rotated about x axis by 90°
Molmil generated image of 4v8g
rotated about y axis by 90°
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