4V5E

Insights into translational termination from the structure of RF2 bound to the ribosome

This is a large structure.

Summary for 4V5E

Related1HR0 2V48 1IBK 2B64 1XMQ 1IBL 2B9M 2UUC 2WDK 1PN8 2WDG 1XNR 1DV4 1HNZ 1RSS 2WDH 2J02 1J5E 1JGQ 2J00 2B9O 1I94 1HNX 1I96 2UU9 1PN7 2UUB 1VOV 1EG0 1IBM 1EMI 2UXB 2VQE 1G1X 1PNX 2V46 2UUA 1I95 1XNQ 1QD7 2VQF 1GIX 1JGO 1JGP 1N32 2F4V 1N34 1N33 1TWT 1PNS 1QZC 2UXD 1FKA 1YL4 2WDM 2UXC 1N36 1FJG 1XMO 1HNW 1I97 1L1U
Integrates2WH1 2WH2 2WH3 2WH4
Descriptor16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... (61 entities in total)
Functional Keywordsribosomal protein, ribonucleoprotein, termination, rrna-binding, trna-binding, metal-binding, rf2, trna, mrna, ribosome, protein biosynthesis, zinc-finger, rna-binding, translation
Biological sourceEscherichia coli K-12
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Cellular locationCytoplasm  Q5SM01
Total number of polymer chains118
Total molecular weight4640998.44
Authors
Weixlbaumer, A.,Jin, H.,Neubauer, C.,Voorhees, R.M.,Petry, S.,Kelley, A.C.,Ramakrishnan, V. (deposition date: 2009-04-30, release date: 2014-07-09, Last modification date: 2018-03-14)
Primary citation
Weixlbaumer, A.,Jin, H.,Neubauer, C.,Voorhees, R.M.,Petry, S.,Kelley, A.C.,Ramakrishnan, V.
Insights Into Translational Termination from the Structure of Rf2 Bound to the Ribosome.
Science, 322:953-956, 2008
PubMed: 18988853 (PDB entries with the same primary citation)
DOI: 10.1126/science.1164840
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.45 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.2573912.6%11.2%7.4%0.55MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4v5e
no rotation
Molmil generated image of 4v5e
rotated about x axis by 90°
Molmil generated image of 4v5e
rotated about y axis by 90°