PDB: 17097 件ウェブページステータス検索Chemie searchBIRD

---

3SMK	Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide and stabilizer Cotylenin A 分子名称: 14-3-3 protein sigma, Cotylenin A, MAGNESIUM ION, ... 著者 Anders, C, Schumacher, B, Ottmann, C. 登録日 2011-06-28 公開日 2012-07-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem. Biol., 20, 2013
3SMN	Crystal structure of human 14-3-3 sigma C38N/N166H in complex with task-3 peptide and stabilizer Fusicoccin A-THF 分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... 著者 Anders, C, Schumacher, B, Ottmann, C. 登録日 2011-06-28 公開日 2012-07-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem. Biol., 20, 2013
3SMJ	Human poly(ADP-ribose) polymerase 14 (Parp14/Artd8) - catalytic domain in complex with a pyrimidine-like inhibitor 分子名称: 2-methyl-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one, GLYCEROL, Poly [ADP-ribose] polymerase 14 著者 Karlberg, T, Moche, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Edwards, A.M, Ekblad, T, Graslund, S, Kouznetsova, E, Nordlund, P, Nyman, T, Thorsell, A.G, Tresaugues, L, Weigelt, J, Schuler, H, Structural Genomics Consortium (SGC) 登録日 2011-06-28 公開日 2011-07-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors. Nat.Biotechnol., 30, 2012
3T3X	1.57 A structure of Friedreich's ataxia frataxin variant R165C 分子名称: Frataxin, mitochondrial, SULFATE ION 著者 Bridwell-Rabb, J, Winn, A.M, Barondeau, D.P. 登録日 2011-07-25 公開日 2011-08-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex. Biochemistry, 50, 2011
6Z7O	Crystal structure of Thioredoxin T from Drosophila melanogaster 分子名称: Thioredoxin-T, ZINC ION 著者 Freier, R, Aragon, E, Baginski, B, Pluta, R, Martin-Malpartida, P, Torner, C, Gonzaez, C, Macias, M. 登録日 2020-05-31 公開日 2020-10-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Structures of the germline-specific Deadhead and thioredoxin T proteins from Drosophila melanogaster reveal unique features among thioredoxins. Iucrj, 8, 2021
3SPK	Tipranavir in Complex with a Human Immunodeficiency Virus Type 1 Protease Variant 分子名称: HIV-1 protease, N-(3-{(1R)-1-[(6R)-4-HYDROXY-2-OXO-6-PHENETHYL-6-PROPYL-5,6-DIHYDRO-2H-PYRAN-3-YL]PROPYL}PHENYL)-5-(TRIFLUOROMETHYL)-2-PYRIDINESULFONAMIDE 著者 Wang, Y, Liu, Z, Brunzelle, J.S, Kovari, I.A, Kovari, L.C. 登録日 2011-07-01 公開日 2011-10-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 The higher barrier of darunavir and tipranavir resistance for HIV-1 protease. Biochem.Biophys.Res.Commun., 412, 2011
3T3T	1.38 A structure of human frataxin variant Q148G 分子名称: Frataxin, mitochondrial, SULFATE ION 著者 Bridwell-Rabb, J, Winn, A.M, Barondeau, D.P. 登録日 2011-07-25 公開日 2011-08-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex. Biochemistry, 50, 2011
3T3K	1.24 A Structure of Friedreich's ataxia frataxin variant Q148R 分子名称: Frataxin, mitochondrial 著者 Bridwell-Rabb, J, Winn, A.M, Barondeau, D.P. 登録日 2011-07-25 公開日 2011-08-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex. Biochemistry, 50, 2011
3SNA	Crystal structure of SARS coronavirus main protease complexed with Ac-NSFSQ-H (soaking) 分子名称: 3C-like proteinase, Peptide aldehyde inhibitor Ac-NSFSQ-H 著者 Zhu, L, Hilgenfeld, R. 登録日 2011-06-29 公開日 2011-09-07 最終更新日 2012-12-12 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Peptide aldehyde inhibitors challenge the substrate specificity of the SARS-coronavirus main protease. Antiviral Res., 92, 2011
6TM5	Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Nek2A substrate at 3.9 angstrom resolution 分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... 著者 Alfieri, C, Barford, D. 登録日 2019-12-03 公開日 2020-02-19 最終更新日 2020-06-17 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 A unique binding mode of Nek2A to the APC/C allows its ubiquitination during prometaphase. Embo Rep., 21, 2020
4C9Z	Crystal structure of Siah1 at 1.95 A resolution 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, E3 UBIQUITIN-PROTEIN LIGASE SIAH1, ... 著者 Rimsa, V, Eadsforth, T.C, Hunter, W.N. 登録日 2013-10-04 公開日 2013-10-16 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Two High-Resolution Structures of the Human E3 Ubiquitin Ligase Siah1. Acta Crystallogr.,Sect.F, 96, 2013
3T2M	Crystal Structure of NaK Channel N68D Mutant 分子名称: POTASSIUM ION, Potassium channel protein 著者 Sauer, D.B, Zeng, W, Raghunathan, S, Jiang, Y. 登録日 2011-07-22 公開日 2011-10-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.953 Å) 主引用文献 Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation. Proc.Natl.Acad.Sci.USA, 108, 2011
4CBN	Crystal structure of Complement Factor D mutant R202A after conventional refinement 分子名称: COMPLEMENT FACTOR D, GLYCEROL 著者 Forneris, F, Burnley, B.T, Gros, P. 登録日 2013-10-15 公開日 2013-12-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Ensemble Refinement Shows Conformational Flexibility in Crystal Structures of Human Complement Factor D Acta Crystallogr.,Sect.D, 70, 2014
3T1C	Crystal Structure of NaK Channel D66Y Mutant 分子名称: POTASSIUM ION, Potassium channel protein 著者 Sauer, D.B, Zeng, W, Raghunathan, S, Jiang, Y. 登録日 2011-07-21 公開日 2011-10-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.802 Å) 主引用文献 Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation. Proc.Natl.Acad.Sci.USA, 108, 2011
3FLG	The PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 beta 分子名称: DNA (cytosine-5)-methyltransferase 3B 著者 Amaya, M.F, Zeng, H, MacKenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Min, J, Wu, H, Structural Genomics Consortium (SGC) 登録日 2008-12-18 公開日 2009-03-31 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of the PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 beta To be Published
3SRC	Structure of Pseudomonas aeruginosa PvdQ bound to NS2028 分子名称: 1,2-ETHANEDIOL, 8-bromo-4H-[1,2,4]oxadiazolo[3,4-c][1,4]benzoxazin-1-one, Acyl-homoserine lactone acylase pvdQ 著者 Gulick, A.M, Drake, E.J. 登録日 2011-07-07 公開日 2011-09-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Characterization and High-Throughput Screening of Inhibitors of PvdQ, an NTN Hydrolase Involved in Pyoverdine Synthesis. Acs Chem.Biol., 6, 2011
3FMO	Crystal structure of the nucleoporin Nup214 in complex with the DEAD-box helicase Ddx19 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DDX19B, GLYCEROL, ... 著者 Napetschnig, J, Debler, E.W, Blobel, G, Hoelz, A. 登録日 2008-12-22 公開日 2009-05-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Structural and functional analysis of the interaction between the nucleoporin Nup214 and the DEAD-box helicase Ddx19. Proc.Natl.Acad.Sci.USA, 106, 2009
3R3L	Structure of NP protein from Lassa AV strain 分子名称: MANGANESE (II) ION, Nucleoprotein, ZINC ION 著者 Perbandt, M, Brunotte, L, Gunther, S, Betzel, C. 登録日 2011-03-16 公開日 2011-09-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.449 Å) 主引用文献 Structure of the Lassa virus nucleoprotein revealed by X-ray crystallography, small-angle X-ray scattering, and electron microscopy. J.Biol.Chem., 286, 2011
3RCJ	Rapid preparation of triazolyl substituted NH-heterocyclic kinase inhibitors via one-pot Sonogashira coupling TMS-deprotection CuAAC sequence 分子名称: 3-(1-benzyl-1H-1,2,3-triazol-4-yl)-1H-pyrrolo[2,3-b]pyridine, 3-phosphoinositide-dependent protein kinase 1 著者 Graedler, U, Dorsch, D, Merkul, E, Klukas, F, Sirrenberg, C, Greiner, H.E, Mueller, T.J.J. 登録日 2011-03-31 公開日 2011-06-15 最終更新日 2012-12-05 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Rapid preparation of triazolyl substituted NH-heterocyclic kinase inhibitors via one-pot Sonogashira coupling-TMS-deprotection-CuAAC sequence. Org.Biomol.Chem., 9, 2011
3R01	The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors 分子名称: 5-bromo-7-methoxy-1-benzofuran-2-carboxylic acid, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase pim-1 著者 Liu, J. 登録日 2011-03-07 公開日 2011-05-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
3R3C	Crystal structure of Arthrobacter sp. strain SU 4-hydroxybenzoyl CoA thioesterase mutant H64A complexed with 4-hydroxyphenacyl CoA 分子名称: 4-HYDROXYPHENACYL COENZYME A, 4-hydroxybenzoyl-CoA thioesterase 著者 Holden, H.M, Thoden, J.B, Song, F, Zhuang, Z, Trujillo, M, Dunaway-Mariano, D. 登録日 2011-03-15 公開日 2012-03-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Catalytic Mechanism of the Hotdog-fold Enzyme Superfamily 4-Hydroxybenzoyl-CoA Thioesterase from Arthrobacter sp. Strain SU. Biochemistry, 51, 2012
6TLJ	Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 3.8 angstrom resolution 分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... 著者 Alfieri, C, Barford, D. 登録日 2019-12-02 公開日 2020-02-19 最終更新日 2020-06-17 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 A unique binding mode of Nek2A to the APC/C allows its ubiquitination during prometaphase. Embo Rep., 21, 2020
3RBM	Crystal structure of Plasmodium vivax geranylgeranylpyrophosphate synthase complexed with BPH -703 分子名称: 3-(2,2-diphosphonoethyl)-1-dodecyl-1H-imidazol-3-ium, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... 著者 Liu, Y.L, No, J.H, Oldfield, E. 登録日 2011-03-29 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity. Proc.Natl.Acad.Sci.USA, 109, 2012
6ZQT	Crystal structure of the RLIP76 Ral binding domain mutant (E427H/Q433L/K440R) in complex with RalB-GMPPNP 分子名称: GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Hurd, C, Brear, P, Revell, J, Ross, S, Mott, H, Owen, D. 登録日 2020-07-10 公開日 2020-11-25 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases. J.Biol.Chem., 296, 2020
3S34	Structure of the 1121B Fab fragment 分子名称: 1121B Fab heavy chain, 1121B Fab light chain, PHOSPHATE ION 著者 Franklin, M.C. 登録日 2011-05-17 公開日 2011-08-24 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Structural Basis for the Function of Two Anti-VEGF Receptor 2 Antibodies. Structure, 19, 2011

<298299300301302303304305306307308309310311312313>