6TM5
Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Nek2A substrate at 3.9 angstrom resolution
Summary for 6TM5
| Entry DOI | 10.2210/pdb6tm5/pdb |
| EMDB information | 10518 |
| Descriptor | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 13, ... (18 entities in total) |
| Functional Keywords | e3 ubiquitin ligase, complex, cell cycle |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 22 |
| Total formula weight | 1277489.91 |
| Authors | Alfieri, C.,Barford, D. (deposition date: 2019-12-03, release date: 2020-02-19, Last modification date: 2020-06-17) |
| Primary citation | Alfieri, C.,Tischer, T.,Barford, D. A unique binding mode of Nek2A to the APC/C allows its ubiquitination during prometaphase. Embo Rep., 21:e49831-e49831, 2020 Cited by PubMed: 32307883DOI: 10.15252/embr.201949831 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.9 Å) |
Structure validation
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