3SMK

Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide and stabilizer Cotylenin A

Summary for 3SMK

• Entry DOI: 10.2210/pdb3smk/pdb
• Related: 2O98 3LW1 3MHR
• Descriptor: 14-3-3 protein sigma, TASK-3 peptide, Cotylenin A, ... (5 entities in total)
• Functional Keywords: helical protein, phosphoprotein, adapter protein, peptide binding protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P31947
• Total number of polymer chains: 2
• Total formula weight: 28066.94

Authors

Anders, C.,Schumacher, B.,Ottmann, C. (deposition date: 2011-06-28, release date: 2012-07-11, Last modification date: 2023-09-13)

• Primary citation: Anders, C.,Higuchi, Y.,Koschinsky, K.,Bartel, M.,Schumacher, B.,Thiel, P.,Nitta, H.,Preisig-Muller, R.,Schlichthorl, G.,Renigunta, V.,Ohkanda, J.,Daut, J.,Kato, N.,Ottmann, C.; A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface.; Chem. Biol., 20:583-593, 2013; PubMed: 23601647; DOI: 10.1016/j.chembiol.2013.03.015

Experimental method

X-RAY DIFFRACTION (2.1 Å)