6TLJ
Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 3.8 angstrom resolution
Summary for 6TLJ
Entry DOI | 10.2210/pdb6tlj/pdb |
EMDB information | 10516 |
Descriptor | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 13, ... (18 entities in total) |
Functional Keywords | e3 ligase, complex, mitotic checkpoint complex, cell cycle |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 23 |
Total formula weight | 1411712.08 |
Authors | Alfieri, C.,Barford, D. (deposition date: 2019-12-02, release date: 2020-02-19, Last modification date: 2020-06-17) |
Primary citation | Alfieri, C.,Tischer, T.,Barford, D. A unique binding mode of Nek2A to the APC/C allows its ubiquitination during prometaphase. Embo Rep., 21:e49831-e49831, 2020 Cited by PubMed: 32307883DOI: 10.15252/embr.201949831 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
Download full validation report