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6TLJ

Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 3.8 angstrom resolution

Summary for 6TLJ
Entry DOI10.2210/pdb6tlj/pdb
EMDB information10516
DescriptorAnaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 13, ... (18 entities in total)
Functional Keywordse3 ligase, complex, mitotic checkpoint complex, cell cycle
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains23
Total formula weight1411712.08
Authors
Alfieri, C.,Barford, D. (deposition date: 2019-12-02, release date: 2020-02-19, Last modification date: 2020-06-17)
Primary citationAlfieri, C.,Tischer, T.,Barford, D.
A unique binding mode of Nek2A to the APC/C allows its ubiquitination during prometaphase.
Embo Rep., 21:e49831-e49831, 2020
Cited by
PubMed: 32307883
DOI: 10.15252/embr.201949831
PDB entries with the same primary citation
Experimental method
Structure validation

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