3GEF
 
 | | Crystal structure of the R482W mutant of lamin A/C | | 分子名称: | Lamin-A/C | | 著者 | Magracheva, E, Kozlov, S, Stuart, C, Wlodawer, A, Zdanov, A. | | 登録日 | 2009-02-25 | | 公開日 | 2009-08-04 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of the lamin A/C R482W mutant responsible for dominant familial partial lipodystrophy (FPLD).
Acta Crystallogr.,Sect.F, 65, 2009
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6WP3
 | | Pyruvate Kinase M2 Mutant-K433Q | | 分子名称: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Nandi, S, Razzaghi, M, Srivastava, D, Dey, M. | | 登録日 | 2020-04-26 | | 公開日 | 2020-10-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Structural basis for allosteric regulation of pyruvate kinase M2 by phosphorylation and acetylation.
J.Biol.Chem., 295, 2020
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3HY2
 | | Crystal Structure of Sulfiredoxin in Complex with Peroxiredoxin I and ATP:Mg2+ | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Peroxiredoxin-1, ... | | 著者 | Jonsson, T.J, Johnson, L.C, Lowther, W.T. | | 登録日 | 2009-06-22 | | 公開日 | 2009-10-06 | | 最終更新日 | 2021-10-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Protein Engineering of the Quaternary Sulfiredoxin-Peroxiredoxin Enzyme-Substrate Complex Reveals the Molecular Basis for Cysteine Sulfinic Acid Phosphorylation
J.Biol.Chem., 284, 2009
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6WP5
 | | Pyruvate Kinase M2 mutant-S37D | | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Nandi, S, Razzaghi, M, Srivastava, D, Dey, M. | | 登録日 | 2020-04-26 | | 公開日 | 2020-09-30 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Structural basis for allosteric regulation of pyruvate kinase M2 by phosphorylation and acetylation.
J.Biol.Chem., 295, 2020
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7PU5
 | | Structure of SFPQ-NONO complex | | 分子名称: | MAGNESIUM ION, Non-POU domain-containing octamer-binding protein, Splicing factor, ... | | 著者 | Fribourg, S. | | 登録日 | 2021-09-28 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.999 Å) | | 主引用文献 | Crystal structure of SFPQ-NONO heterodimer.
Biochimie, 198, 2022
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6XKI
 | | Crystal structure of eIF4A-I in complex with RNA bound to des-MePateA, a pateamine A analog | | 分子名称: | (3S,6Z,8E,11S,15R)-15-amino-3-[(1E,3E,5E)-7-(dimethylamino)-2,5-dimethylhepta-1,3,5-trien-1-yl]-9,11-dimethyl-4,12-dioxa-20-thia-21-azabicyclo[16.2.1]henicosa-1(21),6,8,18-tetraene-5,13-dione, Eukaryotic initiation factor 4A-I, MAGNESIUM ION, ... | | 著者 | Liang, J, Naineni, S.K, Pelletier, J, Nagar, B. | | 登録日 | 2020-06-26 | | 公開日 | 2021-01-06 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | | 主引用文献 | Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A.
Cell Chem Biol, 28, 2021
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7PQ0
 | | Crystal structure of the Burkholderia Lethal Factor 1 (BLF1) C94S inactive mutant in complex with human eIF4A - Crystal form B | | 分子名称: | Burkholderia Lethal Factor 1 (BLF1), Eukaryotic initiation factor 4A-I | | 著者 | Mobbs, G.W, Aziz, A.A, Dix, S.R, Blackburn, G.M, Sedelnikova, S.E, Minshull, T.C, Dickman, M.J, Baker, P.J, Nathan, S, Firdaus-Raih, M, Rice, D.W. | | 登録日 | 2021-09-15 | | 公開日 | 2022-04-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Molecular basis of specificity and deamidation of eIF4A by Burkholderia Lethal Factor 1.
Commun Biol, 5, 2022
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7PPZ
 | | Crystal structure of the Burkholderia Lethal Factor 1 (BLF1) C94S inactive mutant in complex with human eIF4A - Crystal form A | | 分子名称: | Burkholderia Lethal Factor 1 (BLF1), Eukaryotic initiation factor 4A-I | | 著者 | Mobbs, G.W, Aziz, A.A, Dix, S.R, Blackburn, G.M, Sedelnikova, S.E, Minshull, T.C, Dickman, M.J, Baker, P.J, Nathan, S, Firdaus-Raih, M, Rice, D.W. | | 登録日 | 2021-09-15 | | 公開日 | 2022-04-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | Molecular basis of specificity and deamidation of eIF4A by Burkholderia Lethal Factor 1.
Commun Biol, 5, 2022
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5MRG
 | | Solution structure of TDP-43 (residues 1-102) | | 分子名称: | TAR DNA-binding protein 43 | | 著者 | Mompean, M, Romano, V, Pantoja-Uceda, D, Stuani, C, Baralle, F.E, Laurents, D.V. | | 登録日 | 2016-12-22 | | 公開日 | 2017-06-07 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Point mutations in the N-terminal domain of transactive response DNA-binding protein 43 kDa (TDP-43) compromise its stability, dimerization, and functions.
J. Biol. Chem., 292, 2017
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6Y6X
 | | Tetracenomycin X bound to the human ribosome | | 分子名称: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | 著者 | Buschauer, R, Cheng, J, Berninghausen, O, Beckmann, R, Wilson, D.N. | | 登録日 | 2020-02-27 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel.
Nat.Chem.Biol., 16, 2020
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3H6O
 | | Activator-Bound Structure of Human Pyruvate Kinase M2 | | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, 6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one, Pyruvate kinase isozymes M1/M2, ... | | 著者 | Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Inglese, J, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-04-23 | | 公開日 | 2009-05-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Activator-Bound Structures of Human Pyruvate Kinase M2
to be published
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3GR4
 | | Activator-Bound Structure of Human Pyruvate Kinase M2 | | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, 1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Inglese, J, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-03-24 | | 公開日 | 2009-04-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Activator-Bound Structures of Human Pyruvate Kinase M2
to be published
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3GQY
 | | Activator-Bound Structure of Human Pyruvate Kinase M2 | | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, 1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine, L(+)-TARTARIC ACID, ... | | 著者 | Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Inglese, J, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-03-24 | | 公開日 | 2009-04-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Activator-Bound Structures of Human Pyruvate Kinase M2
to be published
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2YT4
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7U0G
 | | structure of LIN28b nucleosome bound 3 OCT4 | | 分子名称: | DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | | 著者 | Lian, T, Guan, R, Bai, Y. | | 登録日 | 2022-02-18 | | 公開日 | 2023-06-28 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
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7U0J
 | | Structure of 162bp LIN28b nucleosome | | 分子名称: | DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | | 著者 | Lian, T, Guan, R, Bai, Y. | | 登録日 | 2022-02-18 | | 公開日 | 2023-06-28 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
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7U0I
 | | Structure of LIN28b nucleosome bound 2 OCT4 | | 分子名称: | DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | | 著者 | Tengfei, L, Guan, R, Bai, Y. | | 登録日 | 2022-02-18 | | 公開日 | 2023-06-28 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
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7U46
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7TRF
 | | Human telomerase catalytic core RNP with H2A/H2B | | 分子名称: | Histone H2A, Histone H2B type 1-C/E/F/G/I, Telomerase RNA, ... | | 著者 | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | | 登録日 | 2022-01-28 | | 公開日 | 2022-04-20 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structure of active human telomerase with telomere shelterin protein TPP1.
Nature, 604, 2022
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7TQL
 | | CryoEM structure of the human 40S small ribosomal subunit in complex with translation initiation factors eIF1A and eIF5B. | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | 著者 | Lapointe, C.P, Grosely, R, Sokabe, M, Alvarado, C, Wang, J, Montabana, E, Villa, N, Shin, B, Dever, T, Fraser, C, Fernandez, I.S, Puglisi, J.D. | | 登録日 | 2022-01-26 | | 公開日 | 2022-04-27 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining.
Nature, 607, 2022
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7U51
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7U50
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7U52
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7TUB
 | | The beta-tubulin folding intermediate IV | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | | 著者 | Zhao, Y, Frydman, J, Chiu, W. | | 登録日 | 2022-02-02 | | 公開日 | 2022-12-28 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT.
Cell, 185, 2022
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7TRG
 | | The beta-tubulin folding intermediate I | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | | 著者 | Zhao, Y, Frydman, J, Chiu, W. | | 登録日 | 2022-01-28 | | 公開日 | 2022-12-28 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT.
Cell, 185, 2022
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