7PQ0

Crystal structure of the Burkholderia Lethal Factor 1 (BLF1) C94S inactive mutant in complex with human eIF4A - Crystal form B

Summary for 7PQ0

• Entry DOI: 10.2210/pdb7pq0/pdb
• Related: 6RRZ
• Descriptor: Burkholderia Lethal Factor 1 (BLF1), Eukaryotic initiation factor 4A-I (2 entities in total)
• Functional Keywords: glutamine deamidase toxin, cysteine protease, eif4a complex, cnf1 family, toxin
• Biological source: Burkholderia pseudomallei (strain K96243); More
• Total number of polymer chains: 2
• Total formula weight: 68490.71

Authors

Mobbs, G.W.,Aziz, A.A.,Dix, S.R.,Blackburn, G.M.,Sedelnikova, S.E.,Minshull, T.C.,Dickman, M.J.,Baker, P.J.,Nathan, S.,Firdaus-Raih, M.,Rice, D.W. (deposition date: 2021-09-15, release date: 2022-04-13, Last modification date: 2024-01-31)

• Primary citation: Mobbs, G.W.,Aziz, A.A.,Dix, S.R.,Blackburn, G.M.,Sedelnikova, S.E.,Minshull, T.C.,Dickman, M.J.,Baker, P.J.,Nathan, S.,Raih, M.F.,Rice, D.W.; Molecular basis of specificity and deamidation of eIF4A by Burkholderia Lethal Factor 1.; Commun Biol, 5:272-272, 2022; PubMed: 35347220; DOI: 10.1038/s42003-022-03186-2

Experimental method

X-RAY DIFFRACTION (3 Å)