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5MRG

Solution structure of TDP-43 (residues 1-102)

Summary for 5MRG
Entry DOI10.2210/pdb5mrg/pdb
NMR InformationBMRB: 34081
DescriptorTAR DNA-binding protein 43 (1 entity in total)
Functional Keywordsstructure from cyana 3.97, dna binding protein
Biological sourceHomo sapiens (Human)
Cellular locationNucleus : Q13148
Total number of polymer chains1
Total formula weight12674.21
Authors
Mompean, M.,Romano, V.,Pantoja-Uceda, D.,Stuani, C.,Baralle, F.E.,Laurents, D.V. (deposition date: 2016-12-22, release date: 2017-06-07, Last modification date: 2017-07-26)
Primary citationMompean, M.,Romano, V.,Pantoja-Uceda, D.,Stuani, C.,Baralle, F.E.,Buratti, E.,Laurents, D.V.
Point mutations in the N-terminal domain of transactive response DNA-binding protein 43 kDa (TDP-43) compromise its stability, dimerization, and functions.
J. Biol. Chem., 292:11992-12006, 2017
Cited by
PubMed: 28566288
DOI: 10.1074/jbc.M117.775965
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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