7U46

Cryo-EM structure of CENP-A nucleosome (palindromic alpha satellite DNA) in complex with CENP-N

Summary for 7U46

• Entry DOI: 10.2210/pdb7u46/pdb
• EMDB information: 26330
• Descriptor: Histone H3-like centromeric protein A, Histone H4, Histone H2A, ... (7 entities in total)
• Functional Keywords: nucleosome, cenp-a, kinetochore, cenp-n, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 11
• Total formula weight: 236579.37

Authors

Zhou, K.,Luger, K. (deposition date: 2022-02-28, release date: 2022-03-16, Last modification date: 2024-02-21)

• Primary citation: Zhou, K.,Gebala, M.,Woods, D.,Sundararajan, K.,Edwards, G.,Krzizike, D.,Wereszczynski, J.,Straight, A.F.,Luger, K.; CENP-N promotes the compaction of centromeric chromatin.; Nat.Struct.Mol.Biol., 29:403-413, 2022; PubMed: 35422519; DOI: 10.1038/s41594-022-00758-y

Experimental method

ELECTRON MICROSCOPY (2.68 Å)