7U50

APE1 bound to a nucleosome core particle with AP-site at SHL-6

Summary for 7U50

• Entry DOI: 10.2210/pdb7u50/pdb
• EMDB information: 26336
• Descriptor: Histone H3.2, Histone H4, Histone H2A type 1, ... (7 entities in total)
• Functional Keywords: nucleosome, dna damage, dna repair, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 11
• Total formula weight: 234857.05

Authors

Weaver, T.M.,Freudenthal, B.D. (deposition date: 2022-03-01, release date: 2022-09-07, Last modification date: 2024-06-12)

• Primary citation: Weaver, T.M.,Hoitsma, N.M.,Spencer, J.J.,Gakhar, L.,Schnicker, N.J.,Freudenthal, B.D.; Structural basis for APE1 processing DNA damage in the nucleosome.; Nat Commun, 13:5390-5390, 2022; PubMed: 36104361; DOI: 10.1038/s41467-022-33057-7

Experimental method

ELECTRON MICROSCOPY (3.4 Å)