PDB: 292 件ウェブページステータス検索Chemie searchBIRD

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5B6G	Protein-protein interaction 分子名称: Adenomatous polyposis coli protein, GLYCEROL, PHQ-ALA-GLY-GLU-ALA-XYC-TYR-GLU, ... 著者 Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J. 登録日 2016-05-27 公開日 2017-05-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration. Nat. Chem. Biol., 13, 2017
7CRU	hnRNPK NLS in complex with Importin alpha 1 (KPNA2) 分子名称: ACETATE ION, GLYCEROL, Heterogeneous nuclear ribonucleoprotein K, ... 著者 Yao, J, Sun, Q. 登録日 2020-08-14 公開日 2021-11-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Nuclear import receptors and hnRNPK mediates nuclear import and stress granule localization of SIRLOIN. Cell.Mol.Life Sci., 78, 2021
2GL7	Crystal Structure of a beta-catenin/BCL9/Tcf4 complex 分子名称: B-cell lymphoma 9 protein, Beta-catenin, Transcription factor 7-like 2 著者 Sampietro, J. 登録日 2006-04-04 公開日 2006-10-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of a beta-Catenin/BCL9/Tcf4 Complex. Mol.Cell, 24, 2006
2JDQ	C-terminal domain of influenza A virus polymerase PB2 subunit in complex with human importin alpha5 分子名称: IMPORTIN ALPHA-1 SUBUNIT, POLYMERASE BASIC PROTEIN 2 著者 Tarendeau, F, Guilligay, D, Mas, P, Boulo, S, Baudin, F, Ruigrok, R.W.H, Hart, D.J, Cusack, S. 登録日 2007-01-11 公開日 2007-02-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure and Nuclear Import Function of the C- Terminal Domain of Influenza Virus Polymerase Pb2 Subunit Nat.Struct.Mol.Biol., 14, 2007
2P8Q	Crystal Structure of human Importin beta bound to the Snurportin1 IBB-domain 分子名称: Importin beta-1 subunit, Snurportin-1 著者 Mitrousis, G, Cingolani, G. 登録日 2007-03-22 公開日 2008-01-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Molecular Basis for the Recognition of Snurportin 1 by Importin {beta}. J.Biol.Chem., 283, 2008
2Q5D	Crystal Structure of Human Importin Beta bound to the Snurportin1 IBB-domain second crystal form 分子名称: Importin beta-1 subunit, Snurportin-1 著者 Mitrousis, G, Cingolani, G. 登録日 2007-05-31 公開日 2008-01-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Molecular Basis for the Recognition of Snurportin 1 by Importin {beta}. J.Biol.Chem., 283, 2008
8HKW	Crystal structure of importin-alpha3 bound to the 53BP1 nuclear localization signal 分子名称: Importin subunit alpha-3, Peptide from TP53-binding protein 1 著者 Matsuura, Y. 登録日 2022-11-28 公開日 2022-12-21 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystallographic data of an importin-alpha 3 dimer in which the two protomers are bridged by a bipartite nuclear localization signal. Data Brief, 47, 2023
7VPS	Crystal structure of the ARM domain of C. glabrata importin alpha 分子名称: Importin subunit alpha 著者 Tan, L, Im, Y.J. 登録日 2021-10-17 公開日 2022-09-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Structural basis for activation of fungal sterol receptor Upc2 and azole resistance. Nat.Chem.Biol., 18, 2022
8HE3	Crystal structure of importin-alpha1 bound to the HIF-1alpha nuclear localization signal (delta 724-751) 分子名称: Hypoxia-inducible factor 1-alpha, Importin subunit alpha-1, SULFATE ION 著者 Matsuura, Y. 登録日 2022-11-07 公開日 2023-02-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of importin-alpha bound to the wild-type and an internal deletion mutant of the bipartite nuclear localization signal of HIF-1 alpha. Biochem.Biophys.Res.Commun., 652, 2023
8HE0	Crystal structure of importin-alpha1 bound to the HIF-1alpha nuclear localization signal (wild-type) 分子名称: Hypoxia-inducible factor 1-alpha, Importin subunit alpha-1 著者 Matsuura, Y. 登録日 2022-11-07 公開日 2023-02-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of importin-alpha bound to the wild-type and an internal deletion mutant of the bipartite nuclear localization signal of HIF-1 alpha. Biochem.Biophys.Res.Commun., 652, 2023
7VPT	Structure of the C. glabrata importin alpha ARM domain - Upc2 NLS fusion 分子名称: C. glabrata importin alpha ARM domain - Upc2 NLS fusion 著者 Tan, L, Im, Y.J. 登録日 2021-10-18 公開日 2022-09-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for activation of fungal sterol receptor Upc2 and azole resistance. Nat.Chem.Biol., 18, 2022
5X8N	Crystal structure of mouse importin-alpha1 bound to the nuclear localization signal of Epstein-Barr virus EBNA-LP protein 分子名称: Epstein-Barr nuclear antigen leader protein, Importin subunit alpha-1 著者 Nakada, R, Matsuura, Y. 登録日 2017-03-03 公開日 2017-04-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of importin-alpha bound to the nuclear localization signal of Epstein-Barr virus EBNA-LP protein Protein Sci., 26, 2017
2C1T	Structure of the Kap60p:Nup2 complex 分子名称: IMPORTIN ALPHA SUBUNIT, NUCLEOPORIN NUP2 著者 Matsuura, Y, Stewart, M. 登録日 2005-09-20 公開日 2005-11-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Nup50/Npap60 Function in Nuclear Import Complex Disassembly and Importin Recycling Embo J., 24, 2005
2C1M	Nup50:importin-alpha complex 分子名称: IMPORTIN-ALPHA2 SUBUNIT, NUCLEOPORIN 50 KDA 著者 Matsuura, Y, Stewart, M. 登録日 2005-09-16 公開日 2005-11-23 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Nup50/Npap60 Function in Nuclear Protein Import Complex Disassembly and Importin Recycling. Embo J., 24, 2005
3IFQ	Interction of plakoglobin and beta-catenin with desmosomal cadherins 分子名称: E-cadherin, SULFATE ION, plakoglobin 著者 Choi, H.-J, Gross, J.C, Pokutta, S, Weis, W.I. 登録日 2009-07-24 公開日 2009-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Interactions of plakoglobin and beta-catenin with desmosomal cadherins: basis of selective exclusion of alpha- and beta-catenin from desmosomes. J.Biol.Chem., 284, 2009
5SVZ	HIV-1 Tat NLS in complex with importin alpha 分子名称: Importin subunit alpha-1, Tat 著者 Smith, K.M, Himiari, Z, Forwood, J.K. 登録日 2016-08-08 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for Importin-alpha Binding of the Human Immunodeficiency Virus Tat. Sci Rep, 7, 2017
1QZ7	Beta-catenin binding domain of Axin in complex with beta-catenin 分子名称: Axin, Beta-catenin 著者 Xing, Y, Clements, W.K, Kimelman, D, Xu, W. 登録日 2003-09-15 公開日 2003-11-18 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of a beta-catenin/Axin complex suggests a mechanism for the {beta}-catenin destruction complex GENES DEV., 17, 2003
1TH1	Beta-catenin in complex with a phosphorylated APC 20aa repeat fragment 分子名称: Adenomatous polyposis coli protein, Beta-catenin 著者 Xing, Y, Clements, W.K, Le Trong, I, Hinds, T.R, Stenkamp, R, Kimelman, D, Xu, W. 登録日 2004-05-31 公開日 2004-09-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of a beta-Catenin/APC Complex Reveals a Critical Role for APC Phosphorylation in APC Function. Mol.Cell, 15, 2004
1V18	The crystal structure of beta-catenin armadillo repeat complexed with a phosphorylated APC 20mer repeat. 分子名称: ADENOMATOUS POLYPOSIS COLI, BETA-CATENIN 著者 Ha, N.-C, Weis, W.I. 登録日 2004-04-09 公開日 2005-01-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Mechanism of Phosphorylation-Dependent Binding of Apc to Beta-Catenin and its Role in Beta-Catenin Degradation Mol.Cell, 15, 2004
4MZ6	Structure of importin-alpha: dUTPase S11E NLS mutant complex 分子名称: Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin subunit alpha-1 著者 Marfori, M, Rona, G, Vertessy, B.G, Kobe, B. 登録日 2013-09-29 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights. Acta Crystallogr.,Sect.D, 69, 2013
1Y2A	Structure of mammalian importin bound to the non-classical PLSCR1-NLS 分子名称: Importin alpha-2 Subunit, decamer fragment of Phospholipid scramblase 1 著者 Chen, M.-H, Ben-Efraim, I, Mitrousis, G, Walker-Kopp, N, Sims, P.J, Cingolani, G. 登録日 2004-11-22 公開日 2005-02-01 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Phospholipid Scramblase 1 Contains a Nonclassical Nuclear Localization Signal with Unique Binding Site in Importin alpha J.Biol.Chem., 280, 2005
4PVZ	Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh2 分子名称: Importin subunit alpha, Inner nuclear membrane protein HEH2 著者 Lokareddy, R.K, Hapsari, A.R, van Rheenen, M, Bhardwaj, A, Veenhoff, L.M, Cingolani, C. 登録日 2014-03-18 公開日 2015-08-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2. Structure, 23, 2015
1T08	Crystal structure of beta-catenin/ICAT helical domain/unphosphorylated APC R3 分子名称: Adenomatous polyposis coli protein, Beta-catenin, Beta-catenin-interacting protein 1 著者 Ha, N.-C, Tonozuka, T, Stamos, J.L, Weis, W.I. 登録日 2004-04-07 公開日 2004-10-12 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation Mol.Cell, 15, 2004
4MZ5	Structure of importin-alpha: dUTPase NLS complex 分子名称: Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin subunit alpha-1 著者 Marfori, M, Rona, G, Vertessy, B.G, Kobe, B. 登録日 2013-09-29 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights. Acta Crystallogr.,Sect.D, 69, 2013
4OIH	Importin Alpha in Complex with the Bipartite NLS of Prp20 分子名称: Guanine nucleotide exchange factor SRM1, Importin subunit alpha-1 著者 Roman, N, Christie, M, Swarbrick, C.M.D, Kobe, B, Forwood, J.K. 登録日 2014-01-19 公開日 2014-02-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Characterisation of the Nuclear Import Receptor Importin Alpha in Complex with the Bipartite NLS of Prp20 Plos One, 8, 2013

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