Crystal Structure of Human Importin Beta bound to the Snurportin1 IBB-domain second crystal form

Summary for 2Q5D

Related2P8Q 1QGK 1UKL
DescriptorImportin beta-1 subunit, Snurportin-1 (2 entities in total)
Functional Keywordsheat repeat, ibb-domain, importin, karyopherin, snurportin, protein transport
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm Q14974
Nucleus O95149
Total number of polymer chains4
Total molecular weight204571.13
Mitrousis, G.,Cingolani, G. (deposition date: 2007-05-31, release date: 2008-01-22, Last modification date: 2014-04-02)
Primary citation
Mitrousis, G.,Olia, A.S.,Walker-Kopp, N.,Cingolani, G.
Molecular Basis for the Recognition of Snurportin 1 by Importin {beta}.
J.Biol.Chem., 283:7877-7884, 2008
PubMed: 18187419 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M709093200
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.30738 1.3% 8.6% 6.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-12-02