8HE0
Crystal structure of importin-alpha1 bound to the HIF-1alpha nuclear localization signal (wild-type)
Summary for 8HE0
| Entry DOI | 10.2210/pdb8he0/pdb |
| Descriptor | Importin subunit alpha-1, Hypoxia-inducible factor 1-alpha (3 entities in total) |
| Functional Keywords | nls, transport protein |
| Biological source | Mus musculus (house mouse) More |
| Total number of polymer chains | 2 |
| Total formula weight | 51119.51 |
| Authors | Matsuura, Y. (deposition date: 2022-11-07, release date: 2023-02-22, Last modification date: 2023-11-29) |
| Primary citation | Matsuura, Y.,Miyawaki, K. Structures of importin-alpha bound to the wild-type and an internal deletion mutant of the bipartite nuclear localization signal of HIF-1 alpha. Biochem.Biophys.Res.Commun., 652:1-5, 2023 Cited by PubMed: 36806083DOI: 10.1016/j.bbrc.2023.02.036 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report
