1TH1
Beta-catenin in complex with a phosphorylated APC 20aa repeat fragment
Summary for 1TH1
Entry DOI | 10.2210/pdb1th1/pdb |
Descriptor | Beta-catenin, Adenomatous polyposis coli protein (3 entities in total) |
Functional Keywords | protein-protein complex, cell adhesion-antitumor protein complex, cell adhesion/antitumor protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P35222 Cell junction, adherens junction: P25054 |
Total number of polymer chains | 4 |
Total formula weight | 155244.70 |
Authors | Xing, Y.,Clements, W.K.,Le Trong, I.,Hinds, T.R.,Stenkamp, R.,Kimelman, D.,Xu, W. (deposition date: 2004-05-31, release date: 2004-09-07, Last modification date: 2023-08-23) |
Primary citation | Xing, Y.,Clements, W.K.,Le Trong, I.,Hinds, T.R.,Stenkamp, R.,Kimelman, D.,Xu, W. Crystal Structure of a beta-Catenin/APC Complex Reveals a Critical Role for APC Phosphorylation in APC Function. Mol.Cell, 15:523-533, 2004 Cited by PubMed: 15327769DOI: 10.1016/j.molcel.2004.08.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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