1TH1
Beta-catenin in complex with a phosphorylated APC 20aa repeat fragment
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0007155 | biological_process | cell adhesion |
| A | 0045296 | molecular_function | cadherin binding |
| B | 0007155 | biological_process | cell adhesion |
| B | 0045296 | molecular_function | cadherin binding |
| C | 0008013 | molecular_function | beta-catenin binding |
| C | 0016055 | biological_process | Wnt signaling pathway |
| C | 0030178 | biological_process | negative regulation of Wnt signaling pathway |
| D | 0008013 | molecular_function | beta-catenin binding |
| D | 0016055 | biological_process | Wnt signaling pathway |
| D | 0030178 | biological_process | negative regulation of Wnt signaling pathway |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| C | SER1371 | |
| C | SER1385 | |
| D | SER1371 | |
| D | SER1385 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q61315 |
| Chain | Residue | Details |
| C | SER1392 | |
| C | SER1395 | |
| D | SER1392 | |
| D | SER1395 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| C | THR1438 | |
| D | THR1438 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine; by PTK6 => ECO:0000269|PubMed:20026641 |
| Chain | Residue | Details |
| A | TYR331 | |
| B | TYR331 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine; by SRC and PTK6 => ECO:0000269|PubMed:22056988, ECO:0000305|PubMed:20026641 |
| Chain | Residue | Details |
| A | TYR333 | |
| B | TYR333 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | SER552 | |
| B | SER552 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18220336 |
| Chain | Residue | Details |
| A | THR556 | |
| B | THR556 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | MOD_RES: S-nitrosocysteine => ECO:0000250|UniProtKB:Q02248 |
| Chain | Residue | Details |
| A | CYS619 | |
| B | CYS619 |
