8HE3
Crystal structure of importin-alpha1 bound to the HIF-1alpha nuclear localization signal (delta 724-751)
Summary for 8HE3
Entry DOI | 10.2210/pdb8he3/pdb |
Related | 8HE0 |
Descriptor | Importin subunit alpha-1, Hypoxia-inducible factor 1-alpha, SULFATE ION, ... (4 entities in total) |
Functional Keywords | nls, transport protein |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 48831.81 |
Authors | Matsuura, Y. (deposition date: 2022-11-07, release date: 2023-02-22, Last modification date: 2023-11-29) |
Primary citation | Matsuura, Y.,Miyawaki, K. Structures of importin-alpha bound to the wild-type and an internal deletion mutant of the bipartite nuclear localization signal of HIF-1 alpha. Biochem.Biophys.Res.Commun., 652:1-5, 2023 Cited by PubMed: 36806083DOI: 10.1016/j.bbrc.2023.02.036 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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