4PVZ

Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh2

Summary for 4PVZ

Entry DOI	10.2210/pdb4pvz/pdb
Related	1BK5 1EE4 1EE5
Descriptor	Importin subunit alpha, Inner nuclear membrane protein HEH2 (3 entities in total)
Functional Keywords	armadillo repeated structure, nuclear import adapter, importin beta, nls-cargos, protein binding
Biological source	Saccharomyces cerevisiae S288c (Baker's yeast) More
Cellular location	Cytoplasm, perinuclear region: Q02821 Nucleus inner membrane ; Single-pass membrane protein : Q03281
Total number of polymer chains	4
Total formula weight	103550.49
Authors	Lokareddy, R.K.,Hapsari, A.R.,van Rheenen, M.,Bhardwaj, A.,Veenhoff, L.M.,Cingolani, C. (deposition date: 2014-03-18, release date: 2015-08-26, Last modification date: 2023-09-20)
Primary citation	Lokareddy, R.K.,Hapsari, R.A.,van Rheenen, M.,Pumroy, R.A.,Bhardwaj, A.,Steen, A.,Veenhoff, L.M.,Cingolani, G. Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2. Structure, 23:1305-1316, 2015 Cited by PubMed: 26051712 DOI: 10.1016/j.str.2015.04.017 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation