PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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6MW9	CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-3 antibody 分子名称: E1, E2, EEEV-3 antibody heavy chain, ... 著者 Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G. 登録日 2018-10-29 公開日 2018-12-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (7.3 Å) 主引用文献 Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization. Cell Rep, 25, 2018
3TPK	Crystal structure of the oligomer-specific KW1 antibody fragment 分子名称: 1,2-ETHANEDIOL, BENZAMIDINE, Immunoglobulin heavy chain antibody variable domain KW1 著者 Parthier, C, Morgado, I, Stubbs, M.T, Fandrich, M. 登録日 2011-09-08 公開日 2012-07-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Molecular basis of beta-amyloid oligomer recognition with a conformational antibody fragment. Proc.Natl.Acad.Sci.USA, 109, 2012
6K0Y	Study of the interactions of a novel monoclonal antibody, mAb059c, with the hPD-1 receptor 分子名称: 1,2-ETHANEDIOL, Antibody Heavy Chain, Antibody Light Chain, ... 著者 Liu, J.X, Wang, G.Q. 登録日 2019-05-08 公開日 2019-12-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Study of the interactions of a novel monoclonal antibody, mAb059c, with the hPD-1 receptor. Sci Rep, 9, 2019
6DF1	Anti-phosphotyrosine antibody 4G10-4D5 Fab complexed with phosphotyrosine peptide 分子名称: Anti-phosphotyrosine antibody 4G10-4D5 heavy chain, Anti-phosphotyrosine antibody 4G10-4D5 light chain, LEU-PTR 著者 Mou, K, Leung, K, Wells, J.A. 登録日 2018-05-13 公開日 2018-11-28 最終更新日 2019-12-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Engineering Improved Antiphosphotyrosine Antibodies Based on an Immunoconvergent Binding Motif. J. Am. Chem. Soc., 140, 2018
3LN9	Crystal structure of the fibril-specific B10 antibody fragment 分子名称: CITRATE ANION, GLYCEROL, Immunoglobulin heavy chain antibody variable domain B10, ... 著者 Parthier, C, Morgado, I, Stubbs, M.T, Faendrich, M. 登録日 2010-02-02 公開日 2010-12-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Amyloid Fibril Recognition with the Conformational B10 Antibody Fragment Depends on Electrostatic Interactions. J.Mol.Biol., 2010
6UUD	Crystal structure of antibody 5D5 in complex with PfCSP N-terminal peptide 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 5D5 Antibody Fab, ... 著者 Thai, E, Scally, S.W, Julien, J.P. 登録日 2019-10-30 公開日 2020-07-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity. J.Exp.Med., 217, 2020
5TIH	Structural basis for inhibition of erythrocyte invasion by antibodies to Plasmodium falciparum protein CyRPA 分子名称: ACETATE ION, CyRPA antibody Fab Heavy Chain, CyRPA antibody Fab Light Chain, ... 著者 Chen, L, Xu, Y, Wang, W, Thompson, J.K, Goddard-Borger, E, Lawrence, M.C, Cowman, A.F. 登録日 2016-10-03 公開日 2017-03-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Structural basis for inhibition of erythrocyte invasion by antibodies toPlasmodium falciparumprotein CyRPA. Elife, 6, 2017
6C5V	An anti-gH/gL antibody that neutralizes dual-tropic infection defines a site of vulnerability on Epstein-Barr virus 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab AMMO1 heavy chain, Antibody Fab AMMO1 light chain, ... 著者 Snijder, J, Ortego, M.S, Weidle, C, Stuart, A.B, Gray, M.A, McElrath, M.J, Pancera, M, Veesler, D, McGuire, A.T, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-01-16 公開日 2018-05-02 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus. Immunity, 48, 2018
8GHP	GUCY2C-ECD bound to anti-GUCY2C-scFv antibody 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Guanylyl cyclase C, anti-GUCY2C-scFv antibody heavy chain, ... 著者 Mosyak, L. 登録日 2023-03-10 公開日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.52 Å) 主引用文献 Molecular insights into recognition of GUCY2C by T-cell engaging bispecific antibody anti-GUCY2CxCD3. Sci Rep, 13, 2023
8GHO	GUCY2C-peptide bound to anti-GUCY2C-scFv antibody 分子名称: Guanylyl cyclase C peptide, anti-GUCY2C-scFv antibody heavy chain, anti-GUCY2C-scFv antibody light chain 著者 Mosyak, L. 登録日 2023-03-10 公開日 2023-08-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Molecular insights into recognition of GUCY2C by T-cell engaging bispecific antibody anti-GUCY2CxCD3. Sci Rep, 13, 2023
6DFI	Crystal structure of anti-Zika antibody Z021 bound to Zika virus envelope protein DIII 分子名称: Zika virus envelope protein DIII, anti-Zika antibody Z021, Heavy Chain, ... 著者 Keeffe, J.R, Bjorkman, P.J. 登録日 2018-05-14 公開日 2018-10-24 最終更新日 2018-11-14 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates. Cell Rep, 25, 2018
6DFJ	Crystal structure of anti-Zika antibody Z021 bound to DENV-1 envelope protein DIII 分子名称: Dengue 1 Envelope DIII domain, anti-Zika antibody Z021, Heavy Chain, ... 著者 Keeffe, J.R, Bjorkman, P.J. 登録日 2018-05-14 公開日 2018-10-24 最終更新日 2018-11-14 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates. Cell Rep, 25, 2018
6TYB	Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... 著者 Gorman, J, Kwong, P.D. 登録日 2019-08-08 公開日 2019-10-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.301 Å) 主引用文献 Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields. Immunity, 51, 2019
8SWW	BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody IF3 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NHP polyclonal antibody IF3 Heavy Chain, ... 著者 Pratap, P.P, Antansijevic, A, Ward, A.B. 登録日 2023-05-19 公開日 2024-05-22 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Priming antibody responses to the fusion peptide in rhesus macaques. Npj Vaccines, 9, 2024
4LAR	Crystal structure of a therapeutic single chain antibody in complex with amphetamine 分子名称: (2S)-1-phenylpropan-2-amine, Single chain antibody fragment scFv6H4 著者 Celical, R, Gokulan, K, Peterson, E.C, Varughese, K.I. 登録日 2013-06-20 公開日 2013-12-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Structural characterization of a therapeutic anti-methamphetamine antibody fragment: oligomerization and binding of active metabolites. Plos One, 8, 2013
6MWC	CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-5 antibody 分子名称: E1, E2, EEEV-5 antibody heavy chain, ... 著者 Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G. 登録日 2018-10-29 公開日 2018-12-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (7.5 Å) 主引用文献 Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization. Cell Rep, 25, 2018
4LAQ	Crystal structure of a therapeutic single chain antibody in the free form 分子名称: D-MALATE, NICKEL (II) ION, SULFATE ION, ... 著者 Celikel, R, Gokulan, K, Peterson, E.C, Varughese, K.I. 登録日 2013-06-20 公開日 2014-01-08 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural characterization of a therapeutic anti-methamphetamine antibody fragment: oligomerization and binding of active metabolites. Plos One, 8, 2013
4LAS	Crystal structure of a therapeutic single chain antibody in complex with 4-hydroxymethamphetamine 分子名称: 4-[(2S)-2-(methylamino)propyl]phenol, Single chain antibody fragment scFv6H4 著者 Celical, R, Gokulan, K, Peterson, E.C, Varughese, K.I. 登録日 2013-06-20 公開日 2013-12-11 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Structural characterization of a therapeutic anti-methamphetamine antibody fragment: oligomerization and binding of active metabolites. Plos One, 8, 2013
6PHF	Pfs25 in complex with the human transmission blocking antibody 2587 分子名称: 25 kDa ookinete surface antigen, 2587 Antibody Fab, Heavy Chain, ... 著者 McLeod, B.R, Julien, J.P. 登録日 2019-06-25 公開日 2019-10-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25. Nat Commun, 10, 2019
7SN3	Structure of human SARS-CoV-2 spike glycoprotein trimer bound by neutralizing antibody C1C-A3 Fab (variable region) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Pan, J, Abraham, J, Shankar, S. 登録日 2021-10-27 公開日 2021-12-08 最終更新日 2022-02-02 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain. Science, 375, 2022
7SN2	Structure of human SARS-CoV-2 neutralizing antibody C1C-A3 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Pan, J, Abraham, J, Yang, P, Shankar, S. 登録日 2021-10-27 公開日 2021-12-08 最終更新日 2022-02-02 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain. Science, 375, 2022
4LKC	An Antibody Against the C-terminal Domain of PCSK9 lowers LDL Cholesterol Levels in vivo 分子名称: Fab fragment of PCSK9 antibody 著者 Schiele, F, Nar, H. 登録日 2013-07-07 公開日 2013-08-14 最終更新日 2014-02-12 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 An Antibody against the C-Terminal Domain of PCSK9 Lowers LDL Cholesterol Levels In Vivo. J.Mol.Biol., 426, 2014
5HGG	Crystal structure of uPA in complex with a camelid-derived antibody fragment 分子名称: (3S)-3-[(2S,3S,4R)-3,4-DIMETHYLTETRAHYDROFURAN-2-YL]BUTYL LAURATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Camelid Derived Antibody Fragment, ... 著者 Yung, K.W.Y, Kromann-Hansen, T, Andreasen, P.A, Ngo, J.C.K. 登録日 2016-01-08 公開日 2016-06-01 最終更新日 2016-08-10 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 A Camelid-derived Antibody Fragment Targeting the Active Site of a Serine Protease Balances between Inhibitor and Substrate Behavior J.Biol.Chem., 291, 2016
6PHH	Unliganded human transmission blocking antibody 2544 分子名称: 2544 Antibody Fab, Heavy Chain, Light Chain, ... 著者 McLeod, B.R, Julien, J.P. 登録日 2019-06-25 公開日 2019-10-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25. Nat Commun, 10, 2019
4GXU	Crystal structure of antibody 1F1 bound to the 1918 influenza hemagglutinin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 1F1, heavy chain, ... 著者 Ekiert, D.C, Wilson, I.A. 登録日 2012-09-04 公開日 2012-12-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.294 Å) 主引用文献 Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses. Plos Pathog., 8, 2012

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