6C5V

An anti-gH/gL antibody that neutralizes dual-tropic infection defines a site of vulnerability on Epstein-Barr virus

Summary for 6C5V

• Entry DOI: 10.2210/pdb6c5v/pdb
• EMDB information: 7344 7345
• Descriptor: Envelope glycoprotein H, Envelope glycoprotein L, Glycoprotein 42, ... (7 entities in total)
• Functional Keywords: epstein-barr virus, neutralizing antibodies, gh/gl, glycoproteins, structural genomics, seattle structural genomics center for infectious disease, ssgcid, viral protein
• Biological source: Human herpesvirus 4 (HHV-4); More
• Total number of polymer chains: 5
• Total formula weight: 167514.83

Authors

Snijder, J.,Ortego, M.S.,Weidle, C.,Stuart, A.B.,Gray, M.A.,McElrath, M.J.,Pancera, M.,Veesler, D.,McGuire, A.T.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2018-01-16, release date: 2018-05-02, Last modification date: 2020-07-29)

• Primary citation: Snijder, J.,Ortego, M.S.,Weidle, C.,Stuart, A.B.,Gray, M.D.,McElrath, M.J.,Pancera, M.,Veesler, D.,McGuire, A.T.; An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus.; Immunity, 48:799-811.e9, 2018; PubMed: 29669253; DOI: 10.1016/j.immuni.2018.03.026

Experimental method

ELECTRON MICROSCOPY (4.8 Å)