6DFI
Crystal structure of anti-Zika antibody Z021 bound to Zika virus envelope protein DIII
Summary for 6DFI
Entry DOI | 10.2210/pdb6dfi/pdb |
Descriptor | anti-Zika antibody Z021, Heavy Chain, anti-Zika antibody Z021, Light Chain, Zika virus envelope protein DIII, ... (4 entities in total) |
Functional Keywords | antibody, fab, zika, dengue, recurrent, neutralizing, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 60538.82 |
Authors | Keeffe, J.R.,Bjorkman, P.J. (deposition date: 2018-05-14, release date: 2018-10-24, Last modification date: 2018-11-14) |
Primary citation | Keeffe, J.R.,Van Rompay, K.K.A.,Olsen, P.C.,Wang, Q.,Gazumyan, A.,Azzopardi, S.A.,Schaefer-Babajew, D.,Lee, Y.E.,Stuart, J.B.,Singapuri, A.,Watanabe, J.,Usachenko, J.,Ardeshir, A.,Saeed, M.,Agudelo, M.,Eisenreich, T.,Bournazos, S.,Oliveira, T.Y.,Rice, C.M.,Coffey, L.L.,MacDonald, M.R.,Bjorkman, P.J.,Nussenzweig, M.C.,Robbiani, D.F. A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates. Cell Rep, 25:1385-1394.e7, 2018 Cited by PubMed: 30403995DOI: 10.1016/j.celrep.2018.10.031 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.48 Å) |
Structure validation
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