6DFI

Crystal structure of anti-Zika antibody Z021 bound to Zika virus envelope protein DIII

Summary for 6DFI

Entry DOI	10.2210/pdb6dfi/pdb
Descriptor	anti-Zika antibody Z021, Heavy Chain, anti-Zika antibody Z021, Light Chain, Zika virus envelope protein DIII, ... (4 entities in total)
Functional Keywords	antibody, fab, zika, dengue, recurrent, neutralizing, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	60538.82
Authors	Keeffe, J.R.,Bjorkman, P.J. (deposition date: 2018-05-14, release date: 2018-10-24, Last modification date: 2018-11-14)
Primary citation	Keeffe, J.R.,Van Rompay, K.K.A.,Olsen, P.C.,Wang, Q.,Gazumyan, A.,Azzopardi, S.A.,Schaefer-Babajew, D.,Lee, Y.E.,Stuart, J.B.,Singapuri, A.,Watanabe, J.,Usachenko, J.,Ardeshir, A.,Saeed, M.,Agudelo, M.,Eisenreich, T.,Bournazos, S.,Oliveira, T.Y.,Rice, C.M.,Coffey, L.L.,MacDonald, M.R.,Bjorkman, P.J.,Nussenzweig, M.C.,Robbiani, D.F. A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates. Cell Rep, 25:1385-1394.e7, 2018 Cited by PubMed: 30403995 DOI: 10.1016/j.celrep.2018.10.031 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.48 Å)

Structure validation