8GHO
GUCY2C-peptide bound to anti-GUCY2C-scFv antibody
Summary for 8GHO
| Entry DOI | 10.2210/pdb8gho/pdb |
| Descriptor | anti-GUCY2C-scFv antibody heavy chain, anti-GUCY2C-scFv antibody light chain, Guanylyl cyclase C peptide, ... (4 entities in total) |
| Functional Keywords | bi-specific antibody gucy2c antigen, protein binding |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 6 |
| Total formula weight | 57442.02 |
| Authors | Mosyak, L. (deposition date: 2023-03-10, release date: 2023-08-30, Last modification date: 2023-10-11) |
| Primary citation | Rampuria, P.,Mosyak, L.,Root, A.R.,Svenson, K.,Agostino, M.J.,LaVallie, E.R. Molecular insights into recognition of GUCY2C by T-cell engaging bispecific antibody anti-GUCY2CxCD3. Sci Rep, 13:13408-13408, 2023 Cited by PubMed: 37591971DOI: 10.1038/s41598-023-40467-0 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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